Genetic factors contribute importantly to the risk of coronary artery disease (CAD), and in the
past decade, there has been major progress in this area. The tools applied include genome …

Background Hypertriglyceridemia (HTG) is a complex trait defined by elevated plasma
triglyceride levels. Genetic determinants of HTG have so far been examined in a piecemeal …

The increasing burden of obesity worldwide and its effect on cardiovascular disease (CVD)
risk is an opportunity for evaluation of preventive approaches. Both obesity and CVD have a …

Objective We aim to analyze the effects of polycyclic aromatic hydrocarbons (PAHs)
exposure and genetic predisposition on blood lipid through a longitudinal epidemiological …

Objective—Fatty acids released via fat cell lipolysis can affect circulating lipid levels.
However, the contribution of different lipolysis measures in adipose tissue is unknown and …

Background Patients with mild-to-moderate hypertriglyceridemia (HTG) are thought to share
specific genetic susceptibility factors that are also present in patients with severe HTG, but …

Abnormal plasma apolipoprotein levels are consistently implicated in CVD risk. Although
30% to 60% of their interindividual variability is genetic, common genetic variants explain …

Copy-number variations (CNVs) have been studied in the context of familial
hypercholesterolemia but have not yet been evaluated in patients with extreme levels of …

CNVs are an important class of mutation that contribute to the molecular genetic
heterogeneity underlying dyslipidemias. Clinical applications of next-generation sequencing …

The etiology of hypertriglyceridemia (HTG) and acute pancreatitis (AP) is complex. Herein,
we dissected the underlying etiology in a patient with HTG and AP. The patient had a 20 …