Hop plant (Humulus lupulus L.) has been used by humans for ages, presumably first as a
herbal remedy, then in the manufacturing of different products, from which beer is the most …

Beyond their role as emulsifiers of lipophilic compounds, bile acids (BAs) are signaling
endocrine molecules that show differential affinity and specificity for a variety of canonical …

Background The gut microbiota contributes to macrophage-mediated inflammation in
adipose tissue with consumption of an obesogenic diet, thus driving the development of …

Xanthohumol (XN), a polyphenol found in the hop plant (Humulus lupulus), has antioxidant,
anti-inflammatory, prebiotic, and anti-hyperlipidemic activity. Preclinical evidence suggests …

The synthesis and metabolism of bile acids (BAs) has been implicated in various metabolic
diseases, including obesity and diabetes. As natural antioxidants, dietary polyphenols play a …

Scope The polyphenol xanthohumol (XN) improves dysfunctional glucose and lipid
metabolism in diet‐induced obesity animal models. Because XN changes intestinal …

Hyperglycemia-associated advanced glycation end products (AGEs) and the receptor for
AGE (RAGE) contribute to nonalcoholic fatty liver disease (NAFLD). Xanthohumol (XH) …

Background Xanthohumol (XN), a bioactive flavonoid from Humulus lupulus with anti-
inflammatory properties, has potential benefits for patients with Crohn's disease (CD), a type …

Bile acids (BAs) affect the growth of potentially pathogenic commensals, including those
from the Enterobacteriaceae family, which are frequently overrepresented in inflammatory …

The prevalence of obesity and related metabolic diseases has increased dramatically
worldwide. As obesity progresses, various lipid species accumulate in ectopic tissues …