Polypharmacy in older adults: a narrative review of definitions, epidemiology and consequences

F Pazan, M Wehling - European geriatric medicine, 2021 - Springer
Background The number of older adults has been constantly growing around the globe.
Consequently, multimorbidity and related polypharmacy have become an increasing …

Polypharmacy, inappropriate prescribing, and deprescribing in older people: through a sex and gender lens

PA Rochon, M Petrovic, A Cherubini… - The Lancet Healthy …, 2021 - thelancet.com
Polypharmacy is very common in older adults and increases the risk of inappropriate and
unsafe prescribing for older adults. Older adults, particularly women (who make up the …

The epidemiology of polypharmacy in older adults: register-based prospective cohort study

L Morin, K Johnell, ML Laroche, J Fastbom… - Clinical …, 2018 - Taylor & Francis
Objective Polypharmacy is the concomitant use of several drugs by a single person, and it
increases the risk of adverse drug-related events in older adults. Little is known about the …

Hospital admissions due to adverse drug reactions in the elderly. A meta-analysis

TJ Oscanoa, F Lizaraso, A Carvajal - European journal of clinical …, 2017 - Springer
Introduction It is currently admitted that adverse drug reactions (ADRs) account for a great
burden of disease. Of particular concern are ADR-induced hospital admissions, particularly …

Association between polypharmacy and death: a systematic review and meta-analysis

N Leelakanok, AL Holcombe, BC Lund, X Gu… - Journal of the American …, 2017 - Elsevier
Objective Polypharmacy has been linked to a myriad of adverse consequences, and
escalating rates of polypharmacy present an emerging concern, particularly among older …

Prevalence and factors associated with polypharmacy in long-term care facilities: a systematic review

N Jokanovic, ECK Tan, MJ Dooley… - Journal of the American …, 2015 - Elsevier
Objective The objective of the study was to investigate the prevalence of, and factors
associated with, polypharmacy in long-term care facilities (LTCFs). Methods MEDLINE …

[HTML][HTML] Prevalence of potentially inappropriate medication use in older adults living in nursing homes: a systematic review

L Morin, ML Laroche, G Texier, K Johnell - Journal of the American Medical …, 2016 - Elsevier
Importance As older adults living in nursing homes are at a high risk of adverse drug-related
events, medications with a poor benefit/risk ratio or with a safer alternative should be …

STOPPFrail (Screening Tool of Older Persons Prescriptions in Frail adults with limited life expectancy): consensus validation

AH Lavan, P Gallagher, C Parsons… - Age and …, 2017 - academic.oup.com
Objective to validate STOPPFrail, a list of explicit criteria for potentially inappropriate
medication (PIM) use in frail older adults with limited life expectancy. Design a Delphi …

Prevalence of adverse drug reactions in the primary care setting: A systematic review and meta-analysis

WN Insani, C Whittlesea, H Alwafi, KKC Man… - PLoS …, 2021 - journals.plos.org
Background Adverse drug reactions (ADRs) represent a major cause of iatrogenic morbidity
and mortality in patient care. While a substantial body of work has been undertaken to …

Explicit criteria as clinical tools to minimize inappropriate medication use and its consequences

D Curtin, PF Gallagher… - Therapeutic advances in …, 2019 - journals.sagepub.com
Polypharmacy and prescribing of potentially inappropriate medications (PIMs) are the key
elements of inappropriate medication use (IMU) in older multimorbid people. IMU is …