The preBötzinger Complex (preBötC), a medullary network critical for breathing, relies on
excitatory interneurons to generate the inspiratory rhythm. Yet, half of preBötC neurons are …

Sleep is a highly conserved phenomenon in endotherms, and therefore it must serve at least
one basic function across this wide range of species. What that function is remains one of …

Abstract Study Objectives Two commentaries recently published in SLEEP came to very
different conclusions regarding how data from a mouse model of sleep-dependent neural …

Lifestyle modification can lead to numerous health issues closely associated with sleep.
Sleep deprivation and disturbances significantly affect inflammation, immunity …

Sleep is essential for optimal cognitive functioning. Although we lack a complete
understanding of the role of sleep in memory consolidation, we know that various factors that …

Good sleep quality and quantity are fundamental to the maintenance of normal physiological
processes. Changes in sleep patterns are commonly observed among young adults and are …

Down syndrome (DS) is a common genetic cause of intellectual disability yet no pro-
cognitive drug therapies are approved for human use. Mechanistic studies in a mouse …

Background Down syndrome (DS, also known as Trisomy 21) is a condition associated with
abnormal neurodevelopment and a higher risk for sleep apnea. Our study sought to better …

Circadian rhythms influence virtually every aspect of behavior. This special issue provides
updates on the current state and future directions for the field of circadian rhythms in …

The propensity for sleep is timed by the circadian system. Many studies have shown that
learning and memory performance is affected by circadian phase. And, of course it is well …