Imaging tumour hypoxia with positron emission tomography
Hypoxia, a hallmark of most solid tumours, is a negative prognostic factor due to its
association with an aggressive tumour phenotype and therapeutic resistance. Given its …
association with an aggressive tumour phenotype and therapeutic resistance. Given its …
[HTML][HTML] PET radiopharmaceuticals for imaging of tumor hypoxia: a review of the evidence
Hypoxia is a pathological condition arising in living tissues when oxygen supply does not
adequately cover the cellular metabolic demand. Detection of this phenomenon in tumors is …
adequately cover the cellular metabolic demand. Detection of this phenomenon in tumors is …
Physics informed neural fields for smoke reconstruction with sparse data
High-fidelity reconstruction of dynamic fluids from sparse multiview RGB videos remains a
formidable challenge, due to the complexity of the underlying physics as well as the severe …
formidable challenge, due to the complexity of the underlying physics as well as the severe …
Over 20% 15N Hyperpolarization in Under One Minute for Metronidazole, an Antibiotic and Hypoxia Probe
Direct NMR hyperpolarization of naturally abundant 15N sites in metronidazole is
demonstrated using SABRE-SHEATH (Signal Amplification by Reversible Exchange in …
demonstrated using SABRE-SHEATH (Signal Amplification by Reversible Exchange in …
Imaging of tumor hypoxia for radiotherapy: current status and future directions
M Busk, J Overgaard, MR Horsman - Seminars in nuclear medicine, 2020 - Elsevier
Tumor regions that are transiently or chronically undersupplied with oxygen (hypoxia) and
nutrients, and enriched with acidic waste products, are common due to an abnormal and …
nutrients, and enriched with acidic waste products, are common due to an abnormal and …
Positron emission tomography imaging sheds new light on hypoxia and antitumor therapies
H Fang, X Wang, X Lan, D Jiang - Interdisciplinary Medicine, 2023 - Wiley Online Library
The effect of the hypoxic tumor microenvironment (TME) on the effectiveness of cancer
treatments has received widespread attention. It is crucial to investigate the mechanisms by …
treatments has received widespread attention. It is crucial to investigate the mechanisms by …
Clinical imaging of hypoxia: Current status and future directions
Tissue hypoxia is a key feature of many important causes of morbidity and mortality. In
pathologies such as stroke, peripheral vascular disease and ischaemic heart disease …
pathologies such as stroke, peripheral vascular disease and ischaemic heart disease …
Head and neck tumor hypoxia imaging by 18F-fluoroazomycin-arabinoside (18F-FAZA)-PET: a review
GB Halmos, LB de Bruin, JA Langendijk… - Clinical nuclear …, 2014 - journals.lww.com
Tumor hypoxia is known to be associated with poor clinical outcome; therefore, patients with
hypoxic tumors might benefit from more intensive treatment approaches. This is particularly …
hypoxic tumors might benefit from more intensive treatment approaches. This is particularly …
Characterization of positron emission tomography hypoxia tracer uptake and tissue oxygenation via electrochemical modeling
SR Bowen, AJ van der Kogel, M Nordsmark… - Nuclear medicine and …, 2011 - Elsevier
PURPOSE: Unique uptake and retention mechanisms of positron emission tomography
(PET) hypoxia tracers make in vivo comparison between them challenging. Differences in …
(PET) hypoxia tracers make in vivo comparison between them challenging. Differences in …
18F-fluoromisonidazole quantification of hypoxia in human cancer patients using image-derived blood surrogate tissue reference regions
M Muzi, LM Peterson, JN O'Sullivan… - Journal of Nuclear …, 2015 - Soc Nuclear Med
18F-fluoromisonidazole (18F-FMISO) is the most widely used PET agent for imaging
hypoxia, a condition associated with resistance to tumor therapy. 18F-FMISO equilibrates in …
hypoxia, a condition associated with resistance to tumor therapy. 18F-FMISO equilibrates in …