Drug repurposing is a strategy used to develop new treatments based on approved or
investigational drugs outside the scope of their original clinical indication. Since this …

Green tea's main polyphenol, epigallocatechin-gallate (EgCg), garners attention for diverse
health-promoting properties. Due to the limited bioavailability of EgCg, drug formulation …

Considering that photodynamic therapy (PDT)-induced oxygen consumption and
microvascular damage could exacerbate hypoxia to drive more glycolysis and …

Background B-raf inhibitors (BRAFi) are effective for BRAF-mutated papillary (PTC) and
anaplastic (ATC) thyroid carcinomas, although acquired resistance impairs tumour cells' …

Diclofenac (DCF) is a non-steroidal anti-inflammatory drug (NSAID), commonly used for the
treatment of pain. It can inhibit prostaglandin synthesis by blocking cyclooxygenase (COX). It …

Gastric cancer (GC) is among the most-diagnosed and deadly malignancies worldwide.
Deregulation in cellular bioenergetics is a hallmark of cancer. Based on the importance of …

Silk fibroin is a biocompatible, non-toxic, mechanically robust protein, and it is commonly
used and studied as a material for biomedical applications. Silk fibroin also gained particular …

The clinical success of immune checkpoint inhibitors (ICIs) has initiated a new era in the
treatment of metastatic cancer. Unfortunately, the overall response rate of ICIs in pretreated …

The electrochemical properties of cytochrome P450 2C9 (CYP2C9) and polymorphic
modifications P450 2C9* 2 (CYP2C9* 2) and P450 2C9* 3 (CYP2C9* 3) were studied. To …

Candida albicans (C. albicans) is a commensal microbiota that resides in humans. However,
in certain cases, C. albicans can infect and cause several diseases to humans. This study …