Rodent models of social stress and neuronal plasticity: Relevance to depressive-like disorders

D Patel, MJ Kas, S Chattarji, B Buwalda - Behavioural brain research, 2019 - Elsevier
Exposure to severe or persistent social stress may lead to the development of psychiatric
disorders such as anxiety and depression. These mood disorders are associated with …

A hypothalamic pathway that suppresses aggression toward superior opponents

D Wei, T Osakada, Z Guo, T Yamaguchi… - Nature …, 2023 - nature.com
Aggression is costly and requires tight regulation. Here we identify the projection from
estrogen receptor alpha-expressing cells in the caudal part of the medial preoptic area …

Excitation-inhibition imbalance in medial preoptic area circuits underlies chronic stress-induced depression-like states

C Tao, GW Zhang, WJ Sun, JJ Huang, LI Zhang… - Nature …, 2024 - nature.com
Dysregulation of brain homeostasis is associated with neuropsychiatric conditions such as
major depressive disorder. However, underlying neural-circuit mechanisms remain not well …

Mechanisms of stress-induced spermatogenesis impairment in male rats following unpredictable chronic mild stress (uCMS)

P Zou, X Wang, W Yang, C Liu, Q Chen… - International journal of …, 2019 - mdpi.com
The negative association between psychological stress and male fertility has been known
for many years. This study was aimed at (i) identifying spermatogenesis impairment induced …

Hypothalamic survival circuits related to social and predatory defenses and their interactions with metabolic control, reproductive behaviors and memory systems

NS Canteras - Current Opinion in Behavioral Sciences, 2018 - Elsevier
Highlights•Distinct hypothalamic circuits respond to different classes of predators.•Metabolic
challenges influence anti-predatory hypothalamic defensive circuits.•Social hypothalamic …

Defensive behaviors and brain regional activation changes in rats confronting a snake

J Mendes-Gomes, SC Motta, RP Bindi… - Behavioural Brain …, 2020 - Elsevier
In the present study, we examined behavioral and brain regional activation changes of rats).
To a nonmammalian predator, a wild rattler snake (Crotalus durissus terrificus). Accordingly …

Role of the rostral dorsomedial column of the periaqueductal gray during social defeat in rats

AP de Almeida, AM Tamais, C Zerbini… - Annals of the New …, 2023 - Wiley Online Library
Previous studies showed that the dorsal premammillary nucleus of the hypothalamus (PMD)
is involved in social passive defensive behaviors likely to be meditated by descending …

Role of CRF1 and CRF2 receptors in the lateral hypothalamus in cardiovascular and anxiogenic responses evoked by restraint stress in rats: Evaluation of acute and …

L Barretto-de-Souza, R Benini, LL Reis-Silva… - …, 2022 - Elsevier
We investigated the role of corticotropin-releasing factor (CRF) neurotransmission within the
lateral hypothalamus (LH) in cardiovascular and anxiogenic-like responses evoked by acute …

Functional lateralization of the medial prefrontal cortex in the modulation of anxiety in mice: Left or right?

NS Costa, MA Vicente, AC Cipriano, TT Miguel… - …, 2016 - Elsevier
It has been suggested that the left medial prefrontal cortex (LmPFC) has an inhibitory role in
controlling the right mPFC (RmPFC), thereby reducing the deleterious effects of stressors on …

Clozapine prevented social interaction deficits and reduced c-Fos immunoreactivity expression in several brain areas of rats exposed to acute restraint stress

RP de Oliveira, JS de Andrade, M Spina, JV Chamon… - PLoS …, 2022 - journals.plos.org
In the present study, we evaluate the effect of acute restraint stress (15 min) of male Wistar
rats on social interaction measurements and c-Fos immunoreactivity (c-Fos-ir) expression, a …