Designing drugs that can simultaneously interact with multiple targets is a promising
approach for treating complicated diseases. Compared to using combinations of single …

The efficacy of nonsteroidal anti‐inflammatory drugs (NSAIDs) against inflammation, pain,
and fever has been supporting their worldwide use in the treatment of painful conditions and …

Ligand-directed divergent synthesis (LDS) is an important synthetic tool for the preparation
of structurally diverse organic molecules without tedious steps to modify substrates. Herein …

The H-bond promoted electrochemical [2+ 2+ 1] annulation of benzo [d] isothiazole 1, 1-
dioxides, N-arylglycines and paraformaldehyde for the synthesis of various benzo [d] …

Inflammation is closely linked to the abnormal phospholipid metabolism chain of
cyclooxygenase-2/microsomal prostaglandin E 2 synthase-1/prostaglandin E 2 (COX …

Inflammation is favorable in most cases, because it is a kind of body defensive response to
external stimuli; sometimes, inflammation is also harmful, such as attacks on the body's own …

Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit prostanoid formation and represent
prevalent therapeutics for treatment of inflammatory disorders. However, NSAIDs are …

Microsomal prostaglandin E2 synthase (mPGES)-1 is responsible for the massive
prostaglandin E2 (PGE2) formation during inflammation. Increasing evidence reveals …

Comprehensive Summary The Pd‐catalyzed dipolar cycloaddition represents a significant
synthetic strategy for the construction of useful heterocyclic compounds. This study …

Conspectus Inflammation and other common disorders including diabetes, cardiovascular
disease, and cancer are often the result of several molecular abnormalities and are not likely …