The historic term 'histiocytosis' meaning 'tissue cell'is used as a unifying concept for
diseases characterized by pathogenic myeloid cells that share histological features with …

Langerhans-Cell Histiocytosis A spectrum of diseases formerly known as histiocytosis X and
now called Langerhans-cell histiocytosis is characterized by ERK pathway activation …

Histiocytic neoplasms are a heterogeneous group of clonal haematopoietic disorders that
are marked by diverse mutations in the mitogen-activated protein kinase (MAPK) pathway …

Histiocytoses are disorders characterised by inflammation and the accumulation of cells
derived from the monocyte and macrophage lineages, which results in tissue damage …

Histiocytic neoplasms are rare hematologic disorders accounting for less than 1% of cancers
of the soft tissue and lymph nodes. Clinical presentation and prognosis of these disorders …

Histiocytoses are heterogeneous hematopoietic diseases characterized by the accumulation
of CD68 (+) cells with various admixed inflammatory infiltrates. The identification of the …

Langerhans cell histiocytosis (LCH) is a rare myeloid neoplasm mainly affecting young
children. This study aimed to evaluate the outcomes of 449 pediatric patients enrolled in the …

Langerhans cell histiocytosis (LCH) is a rare and clinically heterogeneous hematological
disease characterized by the accumulation of mononuclear phagocytes in various tissues …

Langerhans cell histiocytosis (LCH) is an inflammatory myeloid neoplasia characterized by
granulomatous lesions containing pathological CD207+ dendritic cells (DCs) with …

Central nervous system (CNS) involvement in Langerhans cell histiocytosis (LCH) can
include mass lesions of the hypothalamic pituitary axis, choroid plexus, cerebrum, and …