Controllable photodynamic therapy implemented by regulating singlet oxygen efficiency

W Wu, X Shao, J Zhao, M Wu - Advanced Science, 2017 - Wiley Online Library
With singlet oxygen (1O2) as the active agent, photodynamic therapy (PDT) is a promising
technique for the treatment of various tumors and cancers. But it is hampered by the poor …

The investigation of unique water-soluble heptamethine cyanine dye for use as NIR photosensitizer in photodynamic therapy of cancer cells

X Yang, J Bai, Y Qian - Spectrochimica Acta Part A: Molecular and …, 2020 - Elsevier
In this paper, a unique water-soluble heptamethine cyanine dye as NIR photosensitizer was
synthesized to explore its properties associated with potential applications in photodynamic …

Enhancing Precision in Photodynamic Therapy: Innovations in Light-Driven and Bioorthogonal Activation

NS Kuzmina, EA Fedotova, P Jankovic, GP Gribova… - Pharmaceutics, 2024 - mdpi.com
Over the past few decades, photodynamic therapy (PDT) has evolved as a minimally
invasive treatment modality offering precise control over cancer and various other diseases …

Design, synthesis and biological evaluation of amino organophosphorus imidazoles as a new type of potential antimicrobial agents

WW Gao, S Rasheed, VKR Tangadanchu, Y Sun… - Science China …, 2017 - Springer
A series of amino organophosphorus imidazoles were designed and synthesized as a novel
structural type of antimicrobial agents. Bioactive evaluation in vitro showed that compound 3f …

Dual-Activated Nano-Prodrug for Chemo-Photodynamic Combination Therapy of Breast Cancer

Z Lu, G Xu, X Yang, S Liu, Y Sun, L Chen… - International Journal of …, 2022 - mdpi.com
Herein, we developed a dual-activated prodrug, BTC, that contains three functional
components: a glutathione (GSH)-responsive BODIPY-based photosensitizer with a …

[HTML][HTML] 3D integration of pH-cleavable drug-hydrogel conjugates on magnetically driven smart microtransporters

R Bernasconi, E Mauri, A Rossetti, S Rimondo… - Materials & Design, 2021 - Elsevier
Targeted drug delivery is currently emerging as a promising approach to overcome the limits
of currently employed administration techniques. The most convenient methodology to …

[HTML][HTML] Listeria innocua Dps as a nanoplatform for bioluminescence based photodynamic therapy utilizing Gaussia princeps luciferase and zinc protoporphyrin IX

AW Al-Ani, L Zhang, L Ferreira, L Turyanska… - … , Biology and Medicine, 2019 - Elsevier
Listeria innocua DNA binding protein from starved cells (LiDps) belongs to the ferritin family
and provides a promising self-assembling spherical 12-mer protein scaffold for the …

Singlet Oxygen Activatable Prodrugs of Paclitaxel, SN‐38, MMC and CA4: Nonmitochondria‐Targeted Prodrugs

KMM Rahman, P Thapa, R Hurst… - Photochemistry and …, 2022 - Wiley Online Library
We established a light‐activatable prodrug strategy that produces the combination effect of
photodynamic therapy (PDT) and site‐specific chemotherapy. Prodrugs are activated by …

The synthesis and electrochemical characterization of new metallophthalocyanines containing 4-aminoantipyrine moieties on peripherally positions

B Ertem, G Sarkı, H Yalazan, Z Bıyıklıoğlu… - Inorganica Chimica …, 2017 - Elsevier
The electrochemical characterization and synthetic procedures of novel
metallophthalocyanines (Co, Cu and Mn) 5, 6 and 7 fused eight N-(2, 3-dihydro-1, 5 …

Synthesis, spectroscopic studies and biological evaluation of acridine derivatives: The role of aggregation on the photodynamic efficiency

C Felip-León, O Martinez-Arroyo, S Diaz-Oltra… - Bioorganic & Medicinal …, 2018 - Elsevier
Two new photoactive compounds (1 and 2) derived from the 9-amidoacridine chromophore
have been synthesized and fully characterized. Their abilities to produce singlet oxygen …