All organisms, from simple invertebrates to complex human beings, exist in different colors
and patterns, which arise from the unique distribution of pigments throughout the body …

1. Tyrosinase is a copper-containing enzyme responsible for the production of melanin
pigment throughout the phylogenetic spectrum. 2. 2. In mammals, tyrosinase is glycosylated …

This volume covers all aspects of melanin pigmentation, providing a concise,
comprehensive picture of new knowledge gained at the frontiers of research. It draws …

Skin whitening products are commercially available for cosmetic purposes in order to obtain
a lighter skin appearance. They are also utilized for clinical treatment of pigmentary …

Melanocytes and melanoma cells are known to possess receptors for melanocyte
stimulating hormone (MSH). A cDNA clone, designated IID, has been isolated from human …

The significance of melanotropic hormones as physiologic regulators of cutaneous
pigmentation in humans is still controversial. Until recently, no direct effect for melanotropins …

To survive and proliferate in pure culture, human melanocytes require basic fibroblast
growth factor (bFGF) and cAMP. Without these factors, even in the presence of serum, the …

Antioxidants are deemed useful in controlling oxidative stress associated with extrinsic skin
aging and pigmentation disorders. Resveratrol is a polyphenol compound found in many …

Although melanocyte stimulating hormone (MSH) peptides are known to stimulate
pigmentation in man, previous reports suggest that human melanocytes are relatively …

Screening of a lambda gt11 human melanocyte cDNA library with antibodies against
hamster tyrosinase (monophenol, L-dopa: oxygen oxidoreductase, EC 1.14. 18.1) resulted …