Flavin-dependent monooxygenases (FDMOs) are known for their remarkable versatility and
for their crucial roles in various biological processes and applications. Extensive research …

The rapid resistance of pathogens to antibiotics has emerged as a major threat to global
health. Identification of new antibiotic targets is thus needed for developing alternative …

Flavoenzymes can mediate a large variety of oxidation reactions through the activation of
oxygen. However, the O2 activation chemistry of flavin enzymes is not yet fully exploited …

The reversible two-electron interconversion of formate and CO2 is catalyzed by both
nonmetallo-and metallo-formate dehydrogenases (FDHs). The latter group comprises …

Flavoprotein monooxygenases catalyze reactions, including hydroxylation and epoxidation,
involved in the catabolism, detoxification, and biosynthesis of natural substrates and …

The textile industry, with its extensive use of dyes and chemicals, stands out as a significant
source of water pollution. Exposure to certain textile dyes, such as azo dyes and their …

Inspired by Nature's ingenuity, considerable progress has been made in recent years to
develop chemoenzymatic processes by the integration of environmentally friendly feature of …

3-Hydroxyindolenines can be used to access several structural motifs that are featured in
natural products and pharmaceutical compounds, yet the chemical synthesis of 3 …

A single-component flavin-dependent halogenase, AetF, has emerged as an attractive
biocatalyst for catalyzing halogenation. However, its flavin chemistry remains unexplored …

Bacterial luciferase (LuxAB) catalyzes the conversion of reduced flavin mononucleotide
(FMNH⁻), oxygen, and a long-chain aldehyde to oxidized FMN, the corresponding acid and …