Structural and immunological principles leading to chemically synthesized, multiantigenic, multistage, minimal subunit-based vaccine development
Dedicated to the memory of Professors Henry G. Kunkel and Bruce Merrifield (Rockefeller
University, New York), who introduced us to the fascinating worlds of immunology and …
University, New York), who introduced us to the fascinating worlds of immunology and …
Intimate Molecular Interactions of P. falciparum Merozoite Proteins Involved in Invasion of Red Blood Cells and Their Implications for Vaccine Design
LE Rodriguez, H Curtidor, M Urquiza… - Chemical …, 2008 - ACS Publications
Intimate Molecular Interactions of P. falciparum Merozoite Proteins Involved in Invasion of Red
Blood Cells and Their Implications for Vaccine Design | Chemical Reviews ACS ACS …
Blood Cells and Their Implications for Vaccine Design | Chemical Reviews ACS ACS …
Salmonella Typhi outer membrane protein STIV is a potential candidate for vaccine development against typhoid and paratyphoid fever
S Das, R Chowdhury, A Pal, K Okamoto, S Das - Immunobiology, 2019 - Elsevier
Enteric fever, caused by Salmonella enterica serovars, Typhi (S. Typhi) and Paratyphi (S.
Paratyphi) is a major public health challenge for the developing nations. Globally, the …
Paratyphi) is a major public health challenge for the developing nations. Globally, the …
Strategies for developing multi‐epitope, subunit‐based, chemically synthesized anti‐malarial vaccines
ME Patarroyo, G Cifuentes, A Bermudez… - Journal of cellular …, 2008 - Wiley Online Library
• Introduction• P. falciparum invasion of RBCs• Merozoite proteins involved in invading
erythrocytes• Erythrocyte proteins involved in merozoite invasion• The state of current …
erythrocytes• Erythrocyte proteins involved in merozoite invasion• The state of current …
A recombinant protein of Salmonella Typhi induces humoral and cell-mediated immune responses including memory responses
Gram negative enteric bacteria, Salmonella enterica serovar Typhi (S. Typhi), the etiological
agent of typhoid fever is a major public health problem in developing countries. While a …
agent of typhoid fever is a major public health problem in developing countries. While a …
[HTML][HTML] Immune protection-inducing protein structures (IMPIPS) against malaria: the weapons needed for beating Odysseus
The review covers the functional and structural approach followed by our group for more
than 34 years in the search for a methodology that allows the rational design of chemically …
than 34 years in the search for a methodology that allows the rational design of chemically …
Gauche+ side-chain orientation as a key factor in the search for an immunogenic peptide mixture leading to a complete fully protective vaccine
A Bermúdez, D Calderon, A Moreno-Vranich… - Vaccine, 2014 - Elsevier
Topological and stereo-electron characteristics are essential in major histocompability class
II–peptide–T–cell receptor (MHC–p–TCR) complex formation for inducing an appropriate …
II–peptide–T–cell receptor (MHC–p–TCR) complex formation for inducing an appropriate …
Shifting the polarity of some critical residues in malarial peptides' binding to host cells is a key factor in breaking conserved antigens' code of silence
G Cifuentes, A Bermudez, R Rodriguez… - Medicinal …, 2008 - ingentaconnect.com
As microbes use many mechanisms for avoiding immunological pressure, new strategies
must be developed to bypass the immunological code of silence of conserved, functionally …
must be developed to bypass the immunological code of silence of conserved, functionally …
Towards the development of a fully protective Plasmodium falciparum antimalarial vaccine
ME Patarroyo, A Bermudez… - Expert Review of …, 2012 - Taylor & Francis
If ever there were a truism then it would be that a completely protective Plasmodium
falciparum malaria vaccine is desperately needed. Our institute has devoted all its efforts …
falciparum malaria vaccine is desperately needed. Our institute has devoted all its efforts …
Structural modifications to a high-activity binding peptide located within the PfEMP1 NTS domain induce protection against P. falciparum malaria in Aotus monkeys
H Curtidor, MH Torres, MP Alba, ME Patarroyo - 2007 - degruyter.com
Binding of P. falciparum-infected erythrocytes to vascular endothelium and to uninfected
erythrocytes is mediated by the parasite-derived variant erythrocyte membrane protein …
erythrocytes is mediated by the parasite-derived variant erythrocyte membrane protein …