The growth hormone (GH)-insulin-like growth factor-1 (IGF1) signaling pathway emerged in
recent years as a key determinant of aging and longevity. Disruption of this network in …

MicroRNAs (miRNAs) are small non-coding RNAs that directly bind to the 3'untranslated
region (3'-UTR) of the target mRNAs to inhibit their expression. The miRNA-29s (miR-29s) …

Glioblastoma (GBM) is the most aggressive brain tumor, and despite initial response to
chemo-and radio-therapy, the persistence of glioblastoma stem cells (GSCs) unfortunately …

Pancreatic ductal adenocarcinoma (PDAC), a prominent cause of cancer deaths worldwide,
is a highly aggressive cancer most frequently detected at an advanced stage that limits …

Pancreatic cancer (PC) is one of the most malignant tumors with a dismal survival rate, this
is primarily due to inevitable chemoresistance. Dysfunctional tyrosine kinases (TKs) and …

Background Enhancing the diagnostic efficacy of early-stage lung cancer is crucial for
improving prognosis. The objective of this study was to ascertain dependable exosomal …

Abstract MicroRNA‑145‑5p (miRNA‑145‑5p) is a short non‑coding RNA located at
chromosome 5q33. 1, which has gained significant attention in several aspects of cellular …

Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive and lethal forms of
cancer. The symptoms appear in advanced stages, and diagnostic and prognostic tests for …

Pancreatic adenocarcinoma (PAAD) is one of the most hazardous cancers in digestive
system, and the prognosis is notoriously bad. Increasing evidences indicate that Laminin …

Simple Summary Ewing sarcoma is an uncommon cancer that arises in mesenchymal
tissues and represents the second most widespread malignant bone neoplasm after …