Childhood asthma phenotypes and endotypes: a glance into the mosaic
F Foppiano, B Schaub - Molecular and Cellular Pediatrics, 2023 - Springer
Background Asthma is an inflammatory lung disease that constitutes the most common
noncommunicable chronic disease in childhood. Childhood asthma shows large …
noncommunicable chronic disease in childhood. Childhood asthma shows large …
The CAR-HEMATOTOX score as a prognostic model of toxicity and response in patients receiving BCMA-directed CAR-T for relapsed/refractory multiple myeloma
Abstract Background BCMA-directed CAR T-cell therapy (CAR-T) has altered the treatment
landscape of relapsed/refractory (r/r) multiple myeloma, but is hampered by unique side …
landscape of relapsed/refractory (r/r) multiple myeloma, but is hampered by unique side …
The Octadecanoids: Synthesis and Bioactivity of 18-Carbon Oxygenated Fatty Acids in Mammals, Bacteria, and Fungi
J Revol-Cavalier, A Quaranta, JW Newman… - Chemical …, 2024 - ACS Publications
The octadecanoids are a broad class of lipids consisting of the oxygenated products of 18-
carbon fatty acids. Originally referring to production of the phytohormone jasmonic acid, the …
carbon fatty acids. Originally referring to production of the phytohormone jasmonic acid, the …
Nasopharyngeal lipidomic endotypes of infants with bronchiolitis and risk of childhood asthma: a multicentre prospective study
Background Bronchiolitis is the leading cause of hospitalisation of US infants and an
important risk factor for childhood asthma. Recent evidence suggests that bronchiolitis is …
important risk factor for childhood asthma. Recent evidence suggests that bronchiolitis is …
Phenotypically driven subgroups of ASD display distinct metabolomic profiles
Abstract Autism Spectrum Disorder (ASD) is a heterogeneous condition that includes a
broad range of characteristics and associated comorbidities; however, the biology …
broad range of characteristics and associated comorbidities; however, the biology …
Multidisciplinary approach combining food metabolomics and epidemiology identifies meglutol as an important bioactive metabolite in tempe, an Indonesian …
This study introduces a multidisciplinary approach to investigate bioactive food metabolites
often overlooked due to their low concentrations. We integrated an in-house food metabolite …
often overlooked due to their low concentrations. We integrated an in-house food metabolite …
[HTML][HTML] miRNAome-metabolome wide association study reveals effects of miRNA regulation in eosinophilia and airflow obstruction in childhood asthma
Background There are important inter-relationships between miRNAs and metabolites:
alterations in miRNA expression can be induced by various metabolic stimuli, and miRNAs …
alterations in miRNA expression can be induced by various metabolic stimuli, and miRNAs …
Metabolomic-derived endotypes of age-related macular degeneration (AMD): a step towards identification of disease subgroups
Age-related macular degeneration (AMD) is a leading cause of blindness worldwide, with a
complex pathophysiology and phenotypic diversity. Here, we apply Similarity Network …
complex pathophysiology and phenotypic diversity. Here, we apply Similarity Network …
Consistent multi-Omic relationships uncover molecular basis of pediatric asthma IgE regulation
Serum total immunoglobulin E levels (total IgE) capture the state of the immune system in
relation to allergic sensitization. High levels are associated with airway obstruction and poor …
relation to allergic sensitization. High levels are associated with airway obstruction and poor …
Metabolite signatures associated with microRNA miR-143-3p serve as drivers of poor lung function trajectories in childhood asthma
Summary Background Lung function trajectories (LFTs) have been shown to be an important
measure of long-term health in asthma. While there is a growing body of metabolomic …
measure of long-term health in asthma. While there is a growing body of metabolomic …