Towards development of a novel universal medical diagnostic method: Raman spectroscopy and machine learning

NM Ralbovsky, IK Lednev - Chemical Society Reviews, 2020 - pubs.rsc.org
Many problems exist within the myriad of currently employed screening and diagnostic
methods. Further, an incredibly wide variety of procedures are used to identify an even …

Raman spectroscopy: A potential diagnostic tool for oral diseases

Y Zhang, L Ren, Q Wang, Z Wen, C Liu… - Frontiers in Cellular and …, 2022 - frontiersin.org
Oral diseases impose a major health burden worldwide and have a profound effect on
general health. Dental caries, periodontal diseases, and oral cancers are the most common …

Diagnostics and therapy assessment using label-free Raman imaging

SF El-Mashtoly, K Gerwert - Analytical Chemistry, 2021 - ACS Publications
Raman microspectroscopy is an emerging analytical tool that can monitor the biochemical
composition of biological or biomedical specimens, including proteins, cells, and tissues, as …

Raman spectral cytopathology for cancer diagnostic applications

D Traynor, I Behl, D O'dea, F Bonnier, S Nicholson… - Nature …, 2021 - nature.com
Raman spectroscopy can provide a rapid, label-free, nondestructive measurement of the
chemical fingerprint of a sample and has shown potential for cancer screening and …

Rapid and noninvasive diagnosis of oral and oropharyngeal cancer based on micro-Raman and FT-IR spectra of saliva

A Falamas, CI Faur, S Ciupe, M Chirila, H Rotaru… - … Acta Part A: Molecular …, 2021 - Elsevier
Fast, sensitive, and noninvasive techniques are needed for better health care management,
particularly when traditional biopsies could be replaced with appropriate analyses of body …

[HTML][HTML] Occurrence of field cancerization in clinically normal oral mucosa: A systematic review and meta-analysis

M Peralta-Mamani, A Terrero-Perez… - Archives of Oral …, 2022 - Elsevier
Objective The purpose was to describe whether there are field cancerization (FC) indicators
in clinically normal mucosa opposite to primary oral squamous cell carcinoma (OSCC) …

Salivary Raman spectroscopy: Understanding alterations in saliva of tobacco habitués and oral cancer subjects

A Hole, P Jadhav, K Pansare, H Noothalapati… - Vibrational …, 2022 - Elsevier
Objective Saliva a non-invasive biofluid, offers diagnostic potential due to its vicinity with
tumour along with systemic pooling of biomarkers. The present study evaluated the …

Surface‐enhanced Raman spectroscopy and multivariate analysis for the diagnosis of oral squamous cell carcinoma

K Wang, Y Qiu, C Wu, ZN Wen… - Journal of Raman …, 2023 - Wiley Online Library
The incidence of oral squamous cell carcinoma (OSCC) is increasing worldwide year by
year, and its prognosis largely depends on early detection. However, it is difficult to make an …

A new look into cancer—a review on the contribution of vibrational spectroscopy on early diagnosis and surgery guidance

AP Mamede, IP Santos, ALM Batista de Carvalho… - Cancers, 2021 - mdpi.com
Simple Summary Cancer is a leading cause of death worldwide, with the detection of the
disease in its early stages, as well as a correct assessment of the tumour margins, being …

Identification of molecular basis for objective discrimination of breast cancer cells (MCF-7) from normal human mammary epithelial cells by Raman microspectroscopy …

K Iwasaki, A Araki, CM Krishna, R Maruyama… - International journal of …, 2021 - mdpi.com
Raman spectroscopy (RS), a non-invasive and label-free method, has been suggested to
improve accuracy of cytological and even histopathological diagnosis. To our knowledge …