An update on the diagnosis, grading, and staging of appendiceal mucinous neoplasms

MA Valasek, RK Pai - Advances in anatomic pathology, 2018 - journals.lww.com
Despite advances in our understanding of appendiceal mucinous neoplasms and their
relationship to the pseudomyxoma peritonei syndrome, the classification of mucinous tumors …

[HTML][HTML] Omics analyses in peritoneal metastasis—utility in the management of peritoneal metastases from colorectal cancer and pseudomyxoma peritonei: a narrative …

C Lund-Andersen, A Torgunrud, KG Fleten… - Journal of …, 2021 - ncbi.nlm.nih.gov
Abstract High-throughput “-omics” analysis may provide a broader and deeper
understanding of cancer biology to define prognostic and predictive biomarkers and identify …

Genome-wide mutational landscape of mucinous carcinomatosis peritonei of appendiceal origin

H Alakus, ML Babicky, P Ghosh, S Yost, K Jepsen… - Genome medicine, 2014 - Springer
Background Mucinous neoplasms of the appendix (MNA) are rare tumors which may
progress from benign to malignant disease with an aggressive biological behavior. MNA is …

Genomic profile of pseudomyxoma peritonei analyzed using next‐generation sequencing and immunohistochemistry

P Nummela, L Saarinen, A Thiel… - … journal of cancer, 2015 - Wiley Online Library
Pseudomyxoma peritonei (PMP) is a relatively rare clinical syndrome characterized by
neoplastic epithelial cells growing in the peritoneal cavity and secreting mucinous ascites …

GNAS is frequently mutated in both low-grade and high-grade disseminated appendiceal mucinous neoplasms but does not affect survival

AD Singhi, JM Davison, HA Choudry, JF Pingpank… - Human pathology, 2014 - Elsevier
We analyzed a series of 55 disseminated appendiceal mucinous neoplasms treated at our
institution for GNAS and KRAS mutations in an attempt to correlate mutation status with …

Molecular profiles of high‐grade and low‐grade pseudomyxoma peritonei

R Noguchi, H Yano, Y Gohda, R Suda, T Igari… - Cancer …, 2015 - Wiley Online Library
Pseudomyxoma peritonei (PMP) is a rare disease exhibiting a distinct clinical feature
caused by cancerous cells that produce mucinous fluid in the abdominal cavity. PMP s …

The biological basis and function of GNAS mutation in pseudomyxoma peritonei: a review

YL Lin, R Ma, Y Li - Journal of Cancer Research and Clinical Oncology, 2020 - Springer
Purpose Pseudomyxoma peritonei (PMP) is a rare clinical malignancy syndrome
characterized by the uncontrollable accumulation of copious mucinous ascites in the …

[HTML][HTML] Pathological prognostic factors of pseudomyxoma peritonei: comprehensive clinicopathological analysis of 155 cases

F Yan, Y Lin, Q Zhou, H Chang, Y Li - Human Pathology, 2020 - Elsevier
Background Pseudomyxoma peritonei (PMP) is an extremely rare malignancy,
characterized by extensive peritoneal implantation and colloidal ascites. This study was to …

[HTML][HTML] Analysis of mutation and loss of heterozygosity by whole-exome sequencing yields insights into pseudomyxoma peritonei

RJ Pengelly, B Rowaiye, K Pickard, B Moran… - The Journal of Molecular …, 2018 - Elsevier
Pseudomyxoma peritonei (PMP) is a clinical syndrome characterized by gross mucinous
ascites originating from a disseminated intraperitoneal neoplasm. Although typically …

The curious case of Gαs gain-of-function in neoplasia

G Innamorati, TM Wilkie, HS Kantheti, MT Valenti… - BMC cancer, 2018 - Springer
Background Mutations activating the α subunit of heterotrimeric Gs protein are associated
with a number of highly specific pathological molecular phenotypes. One of the best …