[HTML][HTML] The boron advantage: the evolution and diversification of boron's applications in medicinal chemistry

K Messner, B Vuong, GK Tranmer - Pharmaceuticals, 2022 - mdpi.com
In this review, the history of boron's early use in drugs, and the history of the use of boron
functional groups in medicinal chemistry applications are discussed. This includes …

Challenges and opportunities for the application of boron clusters in drug design

ZJ Lesnikowski - Journal of medicinal chemistry, 2016 - ACS Publications
There are two branches in boron medicinal chemistry: the first focuses on single boron atom
compounds, and the second utilizes boron clusters. Boron clusters and their heteroatom …

Recent developments with boron as a platform for novel drug design

ZJ Leśnikowski - Expert opinion on drug discovery, 2016 - Taylor & Francis
Introduction: After decades of development, the medicinal chemistry of compounds that
contain a single boron atom has matured to the present status of having equal rights with …

[HTML][HTML] Physiologically active compounds based on membranotropic cage carriers–derivatives of adamantane and polyhedral boron clusters

VV Avdeeva, TM Garaev, EA Malinina… - Russian Journal of …, 2022 - Springer
Data on compounds based on cage structures―boron clusters (polyhedral boron hydrides,
carboranes, metallacarboranes) and compounds of the adamantane series, which possess …

[HTML][HTML] New type of RNA virus replication inhibitor based on decahydro-closo-decaborate anion containing amino acid ester pendant group

VV Avdeeva, TM Garaev, NV Breslav… - JBIC Journal of …, 2022 - Springer
In this work, a synthetic approach to prepare an example of new class of the derivatives of
the closo-decaborate anion with amino acids detached from the boron cluster by pendant …

New nido-carborane-containing conjugates of purine: synthesis and antiviral activity

DA Gruzdev, AA Telegina, VA Ol'shevskaya… - Russian Chemical …, 2022 - Springer
New purine derivatives containing a nido-carborane fragment were synthesized by
nucleophilic substitution of chlorine atom in 6-chloropurine and 2-amino-6-chloropurine …

Anionic polyhedral boron clusters conjugates with 7-diethylamino-4-hydroxycoumarin. Synthesis and lipophilicity determination

A Serdyukov, I Kosenko, A Druzina, M Grin… - Journal of …, 2021 - Elsevier
A series of water-soluble conjugates of 7-diethylamino-4-hydroxycoumarin with four different
anionic polyhedral boron clusters was synthesized. The distribution coefficients (log D 7.4) …

2-Hydroxyethoxy-closo-undecahydrododecaborate (12)([B12H11CH2CH2OH] 2−) as a new prospective reagent for the preparation of closo-dodecaborate building …

J Laskova, A Kozlova, I Ananyev, V Bregadze… - Journal of …, 2017 - Elsevier
Reaction of dioxonium derivative of closo-dodecaborate ([B 12 H 11 O+(CH 2) 4 O]−) with an
access of NaCN in boiling EtOH led to [B 12 H 11 OCH 2 CH 2 OH] 2− with an excellent …

Sonogashira coupling of the ethynyl monocarborane [CB 11 H 11-12-C [triple bond, length as m-dash] CH]−

F Liu, T Chen, K Zhang, T Jiang, J Liu… - Dalton Transactions, 2022 - pubs.rsc.org
The Sonogashira cross coupling between the monocarborane cluster 12-ethynylmonocarba-
closo-dodecaborate [CB11H11-12-CCH]− and bromoarenes under Pd catalysis has been …

Учредители: Российская академия наук, Институт общей и неорганической химии им. НС Курнакова РАН

ЕВ НОВИКОВА, АС ЗАЕВА, ГЛ ДЕНИСОВ… - ЖУРНАЛ …, 2022 - elibrary.ru
Получены и структурно охарактеризованы псевдобиядерный [Bi (S 2 CN i Pr 2) 3] 2 (I) и
1D-псевдополимерный [Bi (S 2 CN i Pr 2) 2][Bi (S 2 CN i Pr 2) Cl 3](II) комплексы висмута …