Recent research has led to novel findings in inflammasome biology and genetics that
altered the diagnosis and management of patients with autoinflammatory syndromes caused …

IL-18 is a proinflammatory and immune regulatory cytokine, member of the IL-1 family. IL-18
was initially identified as an IFN-γ-inducing factor in T and NK cells, involved in Th1 …

In addition to the genomic alterations that occur in malignant cells, the immune system is
increasingly appreciated as a critical axis that regulates the rise of neoplasms and the …

Interleukin-18 (IL-18) is a pro-inflammatory cytokine believed to play a role in a variety of
conditions and diseases including infections, autoimmunity, cancer, diabetes and …

Abstract Summary Interleukin-18 (IL-18, interferon [IFN]-gamma-inducing factor) is a
proinflammatory cytokine converted to a biologically active molecule by interleukin (IL) …

Abstract Interleukin-18 (IL-18) was recently reported to have a pro-tumor effect in various
cancers. Increased IL-18 levels in the serum of cancer patients correlated with malignancy …

ABSTRACT Background: Interleukin-18 (IL-18), a cytokine that plays an important role in the
T-cell-helper response, acts as an angiogenic factor and a tumor suppressor. RANTES …

Cytokines are known to have both stimulatory and inhibitory effects on breast cancer growth
depending on their relative concentrations and the presence of other modulating factors in …

Background: Oral cancer is the leading malignancy in India. Nitric oxide and antioxidant
enzymes play an important role in etiology of oral cancer. Therefore, the present study …

Abstract Background Interleukin (IL)-8 is a proinflammatory cytokine, and high levels of IL-8
are associated with poor prognosis in many malignancies. The objective of this study was to …