Wnt pathway in pancreatic development and pathophysiology

T Napolitano, S Silvano, C Ayachi, M Plaisant… - Cells, 2023 - mdpi.com
The pancreas is an abdominal gland that serves 2 vital purposes: assist food processing by
secreting digestive enzymes and regulate blood glucose levels by releasing endocrine …

Nanodrug Delivery Strategies to Signaling Pathways in Alopecia

X Wu, Y Du - Molecular Pharmaceutics, 2023 - ACS Publications
Over 50% of the global population suffers from hair loss. The mixed results in the treatment
of hair loss reveal the limitations of conventional commercial topical drugs. One the one …

BFNB Enhances Hair Growth in C57BL/6 Mice through the Induction of EGF and FGF7 Factors and the PI3K-AKT-β-Catenin Pathway

S Pérez-Mora, J Ocampo-López… - International Journal of …, 2023 - mdpi.com
The objective of this study was to investigate the potential effects of a formulation derived
from the bioactive fraction of nanostructured Bacopa procumbens (BFNB) on the promotion …

KY19382 Accelerates Cutaneous Wound Healing via Activation of the Wnt/β-Catenin Signaling Pathway

M Yoon, E Kim, SH Seo, GU Kim, KY Choi - International Journal of …, 2023 - mdpi.com
The Wnt/β-catenin signaling pathway plays important roles in the multi-phases of wound
healing: homeostasis, inflammation, proliferative, and remodeling phases. However, there …

CXXC5 Mediates DHT-Induced Androgenetic Alopecia via PGD2

YC Ryu, J Park, YR Kim, S Choi, GU Kim, E Kim… - Cells, 2023 - mdpi.com
The number of people suffering from hair loss is increasing, and hair loss occurs not only in
older men but also in women and young people. Prostaglandin D2 (PGD2) is a well-known …

[HTML][HTML] COX2-ATP Synthase Regulates Spine Follicle Size in Hedgehogs

M Zhang, M Wang, J Jiang, W Liu, S Zhou… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
Skin evolves essential appendages with adaptive patterns that synergistically insulate the
body from environmental insults. How similar appendages in different animals generate …

Hordenine activated dermal papilla cells and promoted hair regrowth by activating Wnt signaling pathway

C Wang, K Zang, Z Tang, T Yang, X Ye, Y Dang - Nutrients, 2023 - mdpi.com
Hordenine is effective in treating hyperpigmentation, fighting diabetes and resisting fibrosis
and acute inflammation. However, the role of Hordenine on hair growth has not been …

Effect of marine-derived saccharides on human skin fibroblasts and dermal papilla cells

A Augustyniak, H McMahon - Marine Drugs, 2023 - mdpi.com
The skin is the largest organ of the human body, composed of a diverse range of cell types,
non-cellular components, and an extracellular matrix. With aging, molecules that are part of …

[HTML][HTML] Novel recombinant R-spondin1 promotes hair regeneration by targeting the Wnt/β-catenin signaling pathway: recombinant R-spondin1 promotes hair …

Y Chen, Z Lu, J Feng, Z Chen, Z Liu… - Acta Biochimica et …, 2023 - ncbi.nlm.nih.gov
Roof plate-specific spondin 1 (R-spondin1, RSPO1) is a Wnt/β-catenin signaling pathway
activator that binds with Wnt ligands to stimulate the Wnt/β-catenin signaling pathway, which …

Glycyrrhizin micellar nanocarriers for topical delivery of baicalin to the hair follicles: A targeted approach tailored for alopecia treatment

Q Zeng, Z Wang, Z Zhu, Y Hu, Y Wang, Y Xue… - International Journal of …, 2022 - Elsevier
Abstract Alopecia affected approximately 16.6% of all people in China, however, treatment
options remain limited due to the side effects. Plant bioactive compound baicalin (BC) …