E Melloul, M Hübner, M Scott, C Snowden… - World journal of …, 2016 - Springer
Abstract Background Enhanced Recovery After Surgery (ERAS) is a multimodal pathway developed to overcome the deleterious effect of perioperative stress after major surgery. In …
Oxidative stress causes damage to multiple cellular components such as DNA, proteins, and lipids, and is implicated in various human diseases including cancer, neurodegeneration …
SA Rushworth, L Zaitseva, MY Murray… - Blood, The Journal …, 2012 - ashpublications.org
Abstract NF-E2–related factor 2 (Nrf2) transcription factor regulates a range of cytoprotective transcriptional responses, preventing further cellular injury by removing biochemical …
L Gao, GE Mann - Cardiovascular research, 2009 - academic.oup.com
Oxidative stress mediated by hyperglycaemia-induced generation of reactive oxygen species (ROS) contributes significantly to the development and progression of diabetes and …
N Wakabayashi, S Shin, SL Slocum, ES Agoston… - Science …, 2010 - science.org
The Keap1-Nrf2-ARE signaling pathway elicits an adaptive response for cell survival after endogenous and exogenous stresses, such as inflammation and carcinogens, respectively …
The Notch signaling pathway enables regulation and control of development, differentiation, and homeostasis through cell-cell communication. Our investigation shows that Notch …
A Safdar, J deBeer, MA Tarnopolsky - Free Radical Biology and Medicine, 2010 - Elsevier
The role of nuclear factor-erythroid 2 p45-related factor 2 (Nrf2) and Kelch-like ECH- associated protein 1 (Keap1) redox signaling has not been characterized in human skeletal …
F Jeddi, N Soozangar, MR Sadeghi, MH Somi… - DNA repair, 2017 - Elsevier
Abstract NF-E2-related factor 2 (Nrf2) protein is a cytosolic transcription factor that regulates antioxidant and stress-related enzymes. Kelch-like ECH-associated protein 1 (Keap1) binds …
In perioperative care after liver resection, transplantation and pancreatoduodenectomy, ERAS (Enhanced Recovery After Surgery) recommendations are based on the reducing …