Ligusticum chuanxiong Hort (known as Chuanxiong in China, CX) is one of the most widely
used and long-standing medicinal herbs in China. Tetramethylpyrazine (TMP) is an alkaloid …

The antitumor efficacy of Chinese herbal medicines has been widely recognized. Leading
compounds such as sterols, glycosides, flavonoids, alkaloids, terpenoids …

With cancer incidence rates continuing to increase and occurrence of resistance in drug
treatment, there is a pressing demand to find safer and more effective anticancer strategy for …

Diabetic foot ulcer (DFU) is a major complication of diabetes and is associated with a high
risk of lower limb amputation and mortality. During their lifetime, 19%–34% of patients with …

Icariin (ICA) is a kind of natural flavonoid compound monomer, which is derived from the
extract of dried stems and leaves of Epimedium. Modern pharmacological studies have …

Lung adenocarcinoma (LUAD) is the most ordinary histological subtype of lung cancer, and
regulatory cell death is an attractive target for cancer therapy. Recent reports suggested that …

Arctium lappa L. is a medicinal edible homologous plant, commonly known as burdock or
bardana, which belongs to the Asteraceae family. It is widely distributed throughout Northern …

Astragalus membranaceus Bunge is widely used in Traditional Chinese Medicine to treat
various cancers. Astragaloside‑IV (AS‑IV) is one of the major compounds isolated from A …

Background HMGB1 and ER stress have been considered to participate in the progression
of pulmonary artery hypertension (PAH). However, the molecular mechanism underlying …

Background: Poria cocos (P. cocos) is an important medicinal fungus in traditional Chinese
medicine. Poria acid (PA), a triterpenoid compound, is an effective component of traditional …