Biomarkers in psychiatry: concept, definition, types and relevance to the clinical reality

MS García-Gutiérrez, F Navarrete, F Sala… - Frontiers in …, 2020 - frontiersin.org
During the last years, an extraordinary effort has been made to identify biomarkers as
potential tools for improving prevention, diagnosis, drug response and drug development in …

Molecular genetics of cocaine use disorders in humans

N Fernandez-Castillo, J Cabana-Dominguez… - Molecular …, 2022 - nature.com
Drug addiction, one of the major health problems worldwide, is characterized by the loss of
control in drug intake, craving, and withdrawal. At the individual level, drugs of abuse …

MicroRNAs in drug addiction: Current status and future perspectives

Y Zhao, F Qin, S Han, S Li, Y Zhao, H Wang… - Pharmacology & …, 2022 - Elsevier
Drug addiction is a chronic and relapsing brain disorder characterized by compulsive drug
seeking and continued drug use despite adverse consequences. The high prevalence and …

Biomarkers of relapse in cocaine use disorder: a narrative review

M Poireau, T Milpied, A Maillard, C Delmaire, E Volle… - Brain Sciences, 2022 - mdpi.com
Introduction: Cocaine use disorder is a chronic disease with severe consequences and a
high relapse rate. There is a critical need to explore the factors influencing relapse in order …

Current and future perspectives of noncoding RNAs in brain function and neuropsychiatric disease

EJ Kyzar, JP Bohnsack, SC Pandey - Biological psychiatry, 2022 - Elsevier
Noncoding RNAs (ncRNAs) represent the majority of the transcriptome and play important
roles in regulating neuronal functions. ncRNAs are exceptionally diverse in both structure …

[HTML][HTML] New paradigms of old psychedelics in schizophrenia

D Mahmood, SK Alenezi, MJ Anwar, F Azam… - Pharmaceuticals, 2022 - mdpi.com
Psychedelics such as lysergic acid diethylamide (LSD), psilocybin (magic mushrooms), and
mescaline exhibit intense effects on the human brain and behaviour. In recent years, there …

MicroRNA-181a is involved in methamphetamine addiction through the ERAD pathway

Y Wang, T Wei, W Zhao, Z Ren, Y Wang… - Frontiers in Molecular …, 2021 - frontiersin.org
The regulation of microRNA (miRNA) is closely related to methamphetamine (METH)
addiction. Past studies have reported that miR-181a is associated with METH addiction, but …

[HTML][HTML] Noncoding RNA therapeutics for substance use disorder

SA Seyednejad, GC Sartor - Advances in drug and alcohol …, 2022 - frontierspartnerships.org
Although noncoding RNAs (ncRNAs) have been shown to regulate maladaptive
neuroadaptations that drive compulsive drug use, ncRNA-targeting therapeutics for …

miRNAs and Substances Abuse: Clinical and Forensic Pathological Implications: A Systematic Review

C Occhipinti, R La Russa, N Iacoponi, J Lazzari… - International Journal of …, 2023 - mdpi.com
Substance addiction is a chronic and relapsing brain disorder characterized by compulsive
seeking and continued substance use, despite adverse consequences. The high prevalence …

Identification of miRNA-mediated gene regulatory networks in L-methionine exposure counteracts cocaine-conditioned place preference in mice

Y Wang, L Yang, H Zhou, K Zhang, M Zhao - Frontiers in Genetics, 2023 - frontiersin.org
Background and Aims: Methionine has been proven to inhibit addictive behaviors of cocaine
dependence. This study aimed to identify the potential mechanisms of MET relating to its …