Metformin is one of the most widely prescribed hypoglycemic drugs and has the potential to
treat many diseases. More and more evidence shows that metformin can regulate the …

Excessive production of inflammatory chemokines and reactive oxygen species (ROS) can
cause a feedback cycle of inflammation response that has a negative effect on cutaneous …

Inflammatory diseases are key contributors to high mortality globally and adversely affect the
quality of life. Current treatments include corticosteroids or nonsteroidal anti-inflammatories …

Photodynamic therapy (PDT) is an important technique to deal with drug-resistant bacterial
infections in the post-antibiotic era. However, the hypoxic environment in intractable …

Diabetic ulcer is a severe complication of diabetes that can lead to amputation due to the
overproduction of pro-inflammatory factors and reactive oxygen species (ROS). In this study …

As the native regenerative potential of adult cardiac tissue is limited post-injury, stimulating
endogenous repair mechanisms in the mammalian myocardium is a potential goal of …

The immune response of the host towards a decellularized scaffold is complex. Not only can
a number of immune cells influence this process, but also the characteristics, preparation …

Oxidative stress is a distinguishing feature in atherosclerosis disease. Reactive oxygen
species (ROS) can increase the oxidized low density lipoprotein (ox-LDL) and oxidative …

The decellularized extracellular matrix (ECM) obtained from human and porcine adipose
tissue (AT) is currently used to prepare regenerative medicine bio-scaffolds. However, the …

Oxidative stress caused by excessive reactive oxygen species (ROS) accumulation
significantly hinders wound healing in patients with diabetes. Scavenging ROS and …