The current tuberculosis (TB) predicament poses numerous challenges and therefore every
incremental scientific work and all positive socio-political engagements, are steps taken in …

Tuberculosis (TB), an infectious disease caused by the bacterium Mycobacterium
tuberculosis (Mtb), has burdened vulnerable populations in modern day societies for …

To curtail pathogens or tumors, antimicrobial or antineoplastic drugs have been developed.
These drugs target microbial/cancer growth and survival, thereby improving the host's …

Several existing molecular tests for multidrug-resistant tuberculosis (MDR-TB) are limited by
complexity and cost, hindering their widespread application. The objective of this proof of …

Pakistan ranks 5th among the world's highest tuberculosis (TB) burden countries alongside
the 6th among countries with the highest burden of drug-resistant TB, including multi-drug …

Rifampicin resistance (RifR) is caused by mutations in rpoB, encoding the β-subunit of RNA
polymerase. RifR mutations generally incur a fitness cost and in resistant isolates are …

Objectives The aim of this study was to determine the MICs of 32 antimicrobial agents for
200 isolates of Rhodococcus equi of animal origin by applying a recently described broth …

Drug-resistant tuberculosis (TB) is a major threat to TB control worldwide. Globally, only 40%
of the 340,000 notified TB patients estimated to have multidrug-resistant-TB (MDR-TB) were …

Coumarin and its derivatives, which are abundant in nature, have a significant role in
medicinal chemistry due to their ability to bind with different targets or receptors. In addition …

Background With the widespread use of rifampicin and isoniazid, bacterial resistance has
become a growing problem. Additionally, the lack of relevant baseline information for the …