Regulatory T cells in tumor microenvironment: new mechanisms, potential therapeutic strategies and future prospects

C Li, P Jiang, S Wei, X Xu, J Wang - Molecular cancer, 2020 - Springer
Regulatory T cells (Tregs) characterized by the expression of the master transcription factor
forkhead box protein p3 (Foxp3) suppress anticancer immunity, thereby hindering protective …

A comprehensive review and update on the pathogenesis of inflammatory bowel disease

Q Guan - Journal of immunology research, 2019 - Wiley Online Library
Inflammatory bowel disease (IBD) is a chronic and life‐threating inflammatory disease of
gastroenteric tissue characterized by episodes of intestinal inflammation. The pathogenesis …

Human FOXP3+ regulatory T cell heterogeneity and function in autoimmunity and cancer

JB Wing, A Tanaka, S Sakaguchi - Immunity, 2019 - cell.com
Regulatory T (Treg) cells expressing the transcription factor Foxp3 have a critical role in the
maintenance of immune homeostasis and prevention of autoimmunity. Recent advances in …

Roles of Porphyromonas gingivalis and its virulence factors in periodontitis

W Xu, W Zhou, H Wang, S Liang - Advances in protein chemistry and …, 2020 - Elsevier
Periodontitis is an infection-driven inflammatory disease, which is characterized by gingival
inflammation and bone loss. Periodontitis is associated with various systemic diseases …

Microbiotas from humans with inflammatory bowel disease alter the balance of gut Th17 and RORγt+ regulatory T cells and exacerbate colitis in mice

GJ Britton, EJ Contijoch, I Mogno, OH Vennaro… - Immunity, 2019 - cell.com
Microbiota are thought to influence the development and progression of inflammatory bowel
disease (IBD), but determining generalizable effects of microbiota on IBD etiology requires …

CD4 and CD8 T lymphocyte interplay in controlling tumor growth

D Ostroumov, N Fekete-Drimusz, M Saborowski… - Cellular and molecular …, 2018 - Springer
The outstanding clinical success of immune checkpoint blockade has revived the interest in
underlying mechanisms of the immune system that are capable of eliminating tumors even …

Th17 and regulatory T cell balance in autoimmune and inflammatory diseases

M Noack, P Miossec - Autoimmunity reviews, 2014 - Elsevier
This review focuses on the biology of T helper 17 (Th17) and regulatory T (Treg) cells and
their role in inflammatory diseases, such as rheumatoid arthritis. Th17 cells represent a pro …

Basic biology and role of interleukin‐17 in immunity and inflammation

C Zenobia, G Hajishengallis - Periodontology 2000, 2015 - Wiley Online Library
Interleukin‐17 (also known as interleukin‐17A) is a key cytokine that links T‐cell activation to
neutrophil mobilization and activation. As such, interleukin‐17 can mediate protective innate …

Foxp3+ T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation

BH Yang, S Hagemann, P Mamareli, U Lauer… - Mucosal …, 2016 - nature.com
Foxp3 (forkhead box P3 transcription factor)-expressing regulatory T cells (Tregs) are
essential for immunological tolerance, best illustrated by uncontrolled effector T-cell …

[PDF][PDF] Chinese society of allergy guidelines for diagnosis and treatment of allergic rhinitis

L Cheng, J Chen, Q Fu, S He, H Li… - Allergy, asthma & …, 2018 - synapse.koreamed.org
Allergic rhinitis (AR) is a global health problem that causes major illnesses and disabilities
worldwide. Epidemiologic studies have demonstrated that the prevalence of AR has …