The roles of COX-2 in protozoan infection

X Wang, J Chen, J Zheng - Frontiers in Immunology, 2023 - frontiersin.org
Protozoan diseases cause great harm in animal husbandry and require human-provided
medical treatment. Protozoan infection can induce changes in cyclooxygenase-2 (COX-2) …

Malaria infection and severe disease risks in Africa

RS Paton, A Kamau, S Akech, A Agweyu, M Ogero… - Science, 2021 - science.org
The relationship between community prevalence of Plasmodium falciparum and the burden
of severe, life-threatening disease remains poorly defined. To examine the three most …

Entire expressed peripheral blood transcriptome in pediatric severe malarial anemia

SB Anyona, Q Cheng, SA Wasena, SW Osata… - Nature …, 2024 - nature.com
This study on severe malarial anemia (SMA: Hb< 6.0 g/dL), a leading global cause of
childhood morbidity and mortality, compares the entire expressed whole blood host …

[HTML][HTML] Long Non-coding RNA Transcripts in Mycobacterium tuberculosis-Host Interactions

M Vijayaraghavan, SS Gadad… - Non-coding RNA …, 2024 - Elsevier
Tuberculosis (TB) persists as a significant health threat, affecting millions of people all over
the world. Despite years of control measures, the elimination of TB has become a difficult …

Human NCR3 gene variants rs2736191 and rs11575837 alter longitudinal risk for development of pediatric malaria episodes and severe malarial anemia

CO Onyango, Q Cheng, EO Munde, E Raballah… - BMC genomics, 2023 - Springer
Background Plasmodium falciparum malaria is a leading cause of pediatric morbidity and
mortality in holoendemic transmission areas. Severe malarial anemia [SMA, hemoglobin …

Complement component 3 mutations alter the longitudinal risk of pediatric malaria and severe malarial anemia

E Raballah, SB Anyona, Q Cheng… - Experimental …, 2022 - journals.sagepub.com
Severe malarial anemia (SMA) is a leading cause of childhood morbidity and mortality in
holoendemic Plasmodium falciparum transmission regions. To gain enhanced …

Nonsynonymous amino acid changes in the α-chain of complement component 5 influence longitudinal susceptibility to Plasmodium falciparum infections and severe …

E Raballah, K Wilding, SB Anyona, EO Munde… - Frontiers in …, 2022 - frontiersin.org
Background: Severe malarial anemia (SMA; Hb< 5.0 g/dl) is a leading cause of childhood
morbidity and mortality in holoendemic Plasmodium falciparum transmission regions such …

Genetic variation in CSF2 (5q31.1) is associated with longitudinal susceptibility to pediatric malaria, severe malarial anemia, and all-cause mortality in a high-burden …

LE Kisia, Q Cheng, E Raballah, EO Munde… - Tropical Medicine and …, 2022 - Springer
Plasmodium falciparum infections remain among the leading causes of morbidity and
mortality in holoendemic transmission areas. Located within region 5q31. 1, the colony …

Differential gene expression in host ubiquitination processes in childhood malarial anemia

SB Anyona, E Raballah, Q Cheng, I Hurwitz… - Frontiers in …, 2021 - frontiersin.org
Background: Malaria remains one of the leading global causes of childhood morbidity and
mortality. In holoendemic Plasmodium falciparum transmission regions, such as western …

Integrative analysis of microRNA and mRNA expression profiles of monocyte-derived dendritic cells differentiation during experimental cerebral malaria

PA Assis, DF Durso, FC Cavalcante… - Journal of Leucocyte …, 2020 - academic.oup.com
Heterogeneity and high plasticity are common features of cells from the mononuclear
phagocyte system: monocytes (MOs), macrophages, and dendritic cells (DCs). Upon …