Super-enhancers: a new frontier for glioma treatment

M Cheng, ZW Zhang, XH Ji, Y Xu, E Bian… - Biochimica et Biophysica …, 2020 - Elsevier
Glioma is the most common primary malignant tumor in the human brain. Although there are
a variety of treatments, such as surgery, radiation and chemotherapy, glioma is still an …

Emerging role of non-coding RNAs in response of cancer cells to radiotherapy

K Ebahimzadeh, H Shoorei, SA Mousavinejad… - … -Research and Practice, 2021 - Elsevier
Radiotherapy is an effective method for treatment of a large proportion of human cancers.
Yet, the efficacy of this method is precluded by the induction of radioresistance in tumor cells …

miR-21 plays a dual role in tumor formation and cytotoxic response in breast tumors

T Dan, AA Shastri, A Palagani, S Buraschi, T Neill… - Cancers, 2021 - mdpi.com
Simple Summary miR-21 is an oncogenic microRNA that has been associated with breast
tumor growth and metastasis in vitro and is also noted to be upregulated by cytotoxic …

MicroRNA-21 maintains hematopoietic stem cell homeostasis through sustaining the nuclear factor-B signaling pathway in mice

M Hu, Y Lu, H Zeng, Z Zhang, S Chen, Y Qi… - …, 2020 - pmc.ncbi.nlm.nih.gov
Long-term hematopoietic output is dependent on hematopoietic stem cell (HSC)
homeostasis which is maintained by a complex molecular network in which microRNA play …

Human exposure to low dose ionizing radiation affects miR-21 and miR-625 expression levels

R Mahmoudi, M Saidijam, S Nikzad, L Tapak… - Molecular Biology …, 2022 - Springer
Background Recently exposure to ionizing radiation driven by artificial radiation sources
such as Medical X-rays and Nuclear medicine has increased hastily. Ionizing radiation …

Bone marrow stromal cell therapy improves survival after radiation injury but does not restore endogenous hematopoiesis

MF Diaz, PD Horton, SP Dumbali, A Kumar… - Scientific Reports, 2020 - nature.com
The only available option to treat radiation-induced hematopoietic syndrome is allogeneic
hematopoietic cell transplantation, a therapy unavailable to many patients undergoing …

Stereotactic body radiation therapy suppresses myeloid-derived suppressor cells by regulating miR-21/Sorbin and SH3 Domain-containing Protein 1 axis

CF Zhao, Q Tang, C Yang, L Zhou… - Human & …, 2024 - journals.sagepub.com
Background Stereotactic body radiation therapy (SBRT) is a targeted form of radiotherapy
used to treat early-stage cancers. Despite its effectiveness, the impact of SBRT on myeloid …

血液发生相关microRNAs 研究进展

孙凤宇, 许强华 - 遗传, 2022 - chinagene.cn
血液发生对生命体有着十分重要的意义. 脊椎动物的血液发生主要表现为造血干细胞的自我更新
和分化, 造血祖细胞的增殖分化以及血细胞的成熟. 血液发生过程的调控涉及多种转录因子 …

[PDF][PDF] 长链非编码RNA FGD5-AS1 通过miR-542-3p/GTPBP4 对肝癌细胞放射敏感性的影响

陈新, 章诺贝 - 暨南大学学报(自然科学与医学版), 2021 - jnxb.jnu.edu.cn
目的: 探讨长链非编码RNAFGD5 AS1 (lncRNAFGD5 AS1) 对肝癌细胞放射敏感性的影响及
其分子机制. 方法: 运用qRT PCR 检测FGD5 AS1, miR 542 3p 和GTPBP4 …

Differential Effects of Microrna-21, 99 and 145 On Lung Regeneration by Putative Stem Cells During Recovery from Influenza Pneumonia

OWJ Joe - 2019 - search.proquest.com
Lung regeneration following influenza pneumonia is a relatively understudied area of
research. Currently, two populations of putative stem cells following influenza pneumonia …