Objectives The frontline drug doxorubicin has been used for treating cancer for over 30
years. While providing a cure in select cases, doxorubicin causes toxicity to most major …

Learning Objectives After completing this course, the reader will be able to: Discuss the
physiology of the different clinical hypersensitivity and infusion reactions to monoclonal …

Nanoxel-PM™, docetaxel-loaded methoxy-poly (ethylene glycol)-block-poly (d, l-
lactide)(mPEG-PDLLA) micellar formulation was prepared in an effort to develop alternative …

Until recently, no effective treatment was available for patients with metastatic malignant
melanoma, and median overall survival was little more than 6 months with the current …

Background The pulmonary side-effects induced by novel antineoplastic agents have not
been well characterized. Methods To further investigate this topic, relevant English and non …

More than 100 drugs are used to treat the many different cancers. They can be divided into
agents with relatively broad, non-targeted specificity and targeted drugs developed on the …

Acute lymphoblastic leukaemia (ALL) is one of the leading types of malignant disorder seen
in children. Viral infections, genetic factors and exposure to chemical carcinogens are some …

Abstract Purpose Hypersensitivity reactions (HSRs) may occur in children with cancer during
the use of almost all chemotherapeutic drugs. HSRs may also produce a negative impact on …

Hypersensitivity reactions to antineoplastic agents are defined as unexpected reactions with
signs and symptoms inconsistent with known toxicity of antineoplastic drugs. These …

Pulmonary toxicity induced by novel antineoplastic agents has not been well characterized
because of the simultaneous or sequential use of drugs and a multimodality therapeutic …