Identifying cancer biomarkers by mass spectrometry‐based glycomics

Y Mechref, Y Hu, A Garcia, A Hussein - Electrophoresis, 2012 - Wiley Online Library
Correlations between aberrant glycosylation and cancer have been established for
decades. The major advances in mass spectrometry (MS) and separation science have …

Borderline ovarian tumors in Sweden 1960–2005: trends in incidence and age at diagnosis compared to ovarian cancer

I Skírnisdóttir, H Garmo, E Wilander… - International journal of …, 2008 - Wiley Online Library
The aim of the study was to investigate long‐term trends in the incidence of borderline
tumors and ovarian cancer in Sweden during 1960–2005, based on data from the …

The preoperative diagnosis of borderline ovarian tumors: a review of current literature

M Morotti, MV Menada, DJ Gillott, PL Venturini… - Archives of gynecology …, 2012 - Springer
Purpose To evaluate the available information on the preoperative diagnosis of borderline
ovarian tumors (BOTs). Methods Articles were identified through electronic databases …

The utility of serum human epididymis protein 4 (HE4) in patients with a pelvic mass

M Montagnana, G Lippi, O Ruzzenente… - Journal of clinical …, 2009 - Wiley Online Library
Aim: Although CA125 is the most widely used cancer marker in the diagnostic approach of
pelvic masses in women, its clinical usefulness is limited because it lacks expression of the …

VEGF induces ascites in ovarian cancer patients via increasing peritoneal permeability by downregulation of Claudin 5

D Herr, A Sallmann, I Bekes, R Konrad, I Holzheu… - Gynecologic …, 2012 - Elsevier
OBJECTIVE: To evaluate the role of VEGF-dependent Claudin 5 production for the
development of ascites via influencing endothelial permeability in peritoneal tissue of …

Serum CA19. 9 levels are commonly elevated in primary ovarian mucinous tumours but cannot be used to predict the histological subtype

PJ Kelly, P Archbold, JH Price, C Cardwell… - Journal of clinical …, 2010 - jcp.bmj.com
Aims CA19. 9 is a monosialoganglioside secreted by mucinous tumours of the
gastrointestinal tract, including the pancreas and biliary tree. Limited studies have shown …

N-Glycosylation of total cellular glycoproteins from the human ovarian carcinoma SKOV3 cell line and of recombinantly expressed human erythropoietin

E Machado, S Kandzia, R Carilho, P Altevogt… - …, 2011 - academic.oup.com
Ovarian carcinoma is the leading cause of death from gynecological cancers in many
Western countries. Aberrant glycosylation is an important aspect in malignant transformation …

Does VEGF facilitate local tumor growth and spread into the abdominal cavity by suppressing endothelial cell adhesion, thus increasing vascular peritoneal …

I Bekes, TWP Friedl, T Köhler, V Möbus, W Janni… - Molecular cancer, 2016 - Springer
Background Ovarian cancer is mostly associated with pathologically regulated permeability
of peritoneal vessels, leading to ascites. Here, we investigated the molecular regulation of …

MRI of borderline epithelial ovarian tumors: Pathologic correlation and diagnostic challenges

T Tsuboyama, K Sato, T Ota, H Fukui, H Onishi… - Radiographics, 2022 - pubs.rsna.org
Borderline epithelial ovarian tumors are a distinct pathologic entity characterized by
increased epithelial proliferation and nuclear atypia, but without frank stromal invasion …

The prognosis predictive score around primary debulking surgery (PPSP) improves diagnostic efficacy in predicting the prognosis of ovarian cancer

N Kawahara, R Kawaguchi, K Waki, T Maehana… - Scientific Reports, 2022 - nature.com
In recent years, the pretreatment inflammatory responses have proven to predict the
prognosis, but no report exists analyzing the combined inflammatory response of the pre …