Frameworks for targeting RNA with small molecules
AU Juru, AE Hargrove - Journal of Biological Chemistry, 2021 - ASBMB
Since the characterization of mRNA in 1961, our understanding of the roles of RNA
molecules has significantly grown. Beyond serving as a link between DNA and proteins …
molecules has significantly grown. Beyond serving as a link between DNA and proteins …
Recent developments in multicomponent synthesis of structurally diversified tetrahydropyridines
MM Khan, S Khan, S Iqbal - RSC advances, 2016 - pubs.rsc.org
Tetrahydropyridines (THPDs) have been recognized as a major constituent of naturally
occurring alkaloids. Being heterocyclic nitrogenous compounds, they therefore display …
occurring alkaloids. Being heterocyclic nitrogenous compounds, they therefore display …
Bismuth nitrate-catalyzed multicomponent reaction for efficient and one-pot synthesis of densely functionalized piperidine scaffolds at room temperature
G Brahmachari, S Das - Tetrahedron Letters, 2012 - Elsevier
A simple, straightforward, and highly efficient diastereoselective multicomponent one-pot
synthesis of a series of pharmaceutically interesting functionalized piperidine derivatives …
synthesis of a series of pharmaceutically interesting functionalized piperidine derivatives …
Synthesis of highly functionalized piperidines by one-pot multicomponent reaction using tetrabutylammonium tribromide (TBATB)
Tetrabutylammonium tribromide (TBATB) has been found to be an efficient catalyst for the
one-pot synthesis of highly substituted piperidines through a combination of 1, 3-dicarbonyl …
one-pot synthesis of highly substituted piperidines through a combination of 1, 3-dicarbonyl …
Iodine catalyzed one-pot five-component reactions for direct synthesis of densely functionalized piperidines
A simple and convenient one-pot multicomponent reaction (MCR) has been developed for
the synthesis of highly functionalized piperidines catalyzed by molecular iodine. This …
the synthesis of highly functionalized piperidines catalyzed by molecular iodine. This …
[HTML][HTML] Robust, highly active, and stable supported Co (ii) nanoparticles on magnetic cellulose nanofiber-functionalized for the multi-component reactions of …
PG Kargar, G Bagherzade - RSC advances, 2021 - pmc.ncbi.nlm.nih.gov
The new recyclable cobalt three-core magnetic catalyst obtained by anchoring a Schiff base
ligand sector and cellulose nanofiber slings on MNP (Fe3O4) was prepared and named as …
ligand sector and cellulose nanofiber slings on MNP (Fe3O4) was prepared and named as …
Five-component domino synthesis of tetrahydropyridines using hexagonal PbCr x Fe12−x O19 as efficient magnetic nanocatalyst
A Sobhani-Nasab, A Ziarati… - Research on Chemical …, 2017 - Springer
Abstract Hexagonal PbCr x Fe 12− x O 19 nanostructures were prepared through a sol–gel
autocombustion (SGAC) method using malonic acid as fuel. Scanning electron microscopy …
autocombustion (SGAC) method using malonic acid as fuel. Scanning electron microscopy …
Camphorsulfonic acid (CSA): An efficient organocatalyst for the synthesis or derivatization of heterocycles with biologically promising activities
G Kaur, K Bala, S Devi, B Banerjee - Current Green Chemistry, 2018 - ingentaconnect.com
Natural product modified organocatalysts have gained attention due to their environmentally
benign and biodegradable nature and as a result, these are now becoming powerful tools …
benign and biodegradable nature and as a result, these are now becoming powerful tools …
Strategies for the design of RNA-binding small molecules
F Aboul-ela - Future medicinal chemistry, 2010 - Taylor & Francis
Bacterial ribosomal RNA is the target of clinically important antibiotics, while biologically
important RNAs in viral and eukaryotic genomes present a range of potential drug targets …
important RNAs in viral and eukaryotic genomes present a range of potential drug targets …
Design, synthesis, molecular docking and in silico ADMET investigations of novel piperidine-bearing cinnamic acid hybrids as potent antimicrobial agents
In order to combat microbial infections and to address the issue of multi-drug resistance, a
class of novel piperidine-bearing cinnamic acid hybrids 4a–4l were synthesized and …
class of novel piperidine-bearing cinnamic acid hybrids 4a–4l were synthesized and …