Assessing and analysing individual differences in change over time is of central scientific
importance to developmental neuroscience. However, the literature is based largely on …

Abstract “The Scaffolding Theory of Aging and Cognition (STAC)”, proposed in 2009, is a
conceptual model of cognitive aging that integrated evidence from structural and functional …

Little is still known about the neuroanatomical substrates related to changes in specific
cognitive abilities in the course of healthy aging, and the existing evidence is predominantly …

Cognitive reserve (CR) is a concept meant to account for the frequent discrepancy between
an individual's measured level of brain pathology and her expected cognitive performance. It …

The myelination of axons by oligodendrocytes has been suggested to be modulated by
experience, which could mediate neural plasticity by optimizing the performance of the …

Episodic memory and working memory decline with advancing age. Nevertheless, large-
scale population-based studies document well-preserved memory functioning in some older …

A substantial corpus of evidence suggests that the cognitive involvement in postural control
and gait increases with aging. A large portion of such studies were based on dual-task …

Human cognitive aging differs between and is malleable within individuals. In the absence
of a strong genetic program, it is open to a host of hazards, such as vascular conditions …

Executive functions (EFs) make possible mentally playing with ideas; taking the time to think
before acting; meeting novel, unanticipated challenges; resisting temptations; and staying …

The biology of CNS remyelination has attracted considerable interest in recent years
because of its translational potential to yield regenerative therapies for the treatment of …