Infection is the second leading cause of death in patients with cancer. Loss of efficacy in
antibiotics due to antibiotic resistance in bacteria is an urgent threat against the continuing …

Background Antimicrobial resistance (AMR) is of public health concern worldwide. Aim We
aimed to summarise the German AMR situation for clinicians and microbiologists. Methods …

Pseudomonas aeruginosa (PA) CbpD belongs to the lytic polysaccharide monooxygenases
(LPMOs), a family of enzymes that cleave chitin or related polysaccharides. Here, we …

Sepsis is a frequent complication in immunosuppressed cancer patients and hematopoietic
stem cell transplant recipients that is associated with high morbidity and mortality rates. The …

Pseudomonas aeruginosa is an aerobic Gram-negative rod-shaped bacterium with a
comparatively large genome and an impressive genetic capability allowing it to grow in a …

Background The optimization of the use of β-lactam antibiotics (BLA) via prolonged infusions
in life-threatening complications such as febrile neutropenia (FN) is still controversial. This …

Background Pseudomonas aeruginosa (PA) bloodstream infection (BSI) is a common
complication in patients with acute leukemia (AL), and the prevalence of antibiotic-resistant …

Carbapenem resistance in difficult-to-treat P. aeruginosa (DTR-PA) strains is primarily
mediated by loss or reduction of the OprD porin, overexpression of the cephalosporinase …

We sought to assess the characteristics and outcomes of neutropenic hematologic patients
with Pseudomonas aeruginosa (PA) bloodstream infection (BSI) treated with ceftolozane …

Objectives: To assess the clinical features and outcomes of Pseudomonas aeruginosa
bloodstream infection (PA BSI) in neutropenic patients with hematological malignancies …