Adipose tissue dysfunction as determinant of obesity-associated metabolic complications

M Longo, F Zatterale, J Naderi, L Parrillo… - International journal of …, 2019 - mdpi.com
Obesity is a critical risk factor for the development of type 2 diabetes (T2D), and its
prevalence is rising worldwide. White adipose tissue (WAT) has a crucial role in regulating …

[HTML][HTML] State of knowledge on molecular adaptations to exercise in humans: historical perspectives and future directions

KM Lavin, PM Coen, LC Baptista, MB Bell… - Comprehensive …, 2022 - ncbi.nlm.nih.gov
For centuries, regular exercise has been acknowledged as a potent stimulus to promote,
maintain, and restore healthy functioning of nearly every physiological system of the human …

In vivo biomolecular imaging of zebrafish embryos using confocal Raman spectroscopy

H Høgset, CC Horgan, JPK Armstrong… - Nature …, 2020 - nature.com
Zebrafish embryos provide a unique opportunity to visualize complex biological processes,
yet conventional imaging modalities are unable to access intricate biomolecular information …

Hijacking of lipid droplets by hepatitis C, dengue and zika viruses—from viral protein moonlighting to extracellular release

APM Cloherty, AD Olmstead, CMS Ribeiro… - International journal of …, 2020 - mdpi.com
Hijacking and manipulation of host cell biosynthetic pathways by human enveloped viruses
are essential for the viral lifecycle. Flaviviridae members, including hepatitis C, dengue and …

[HTML][HTML] Super-resolution microscopy localizes perilipin 5 at lipid droplet-mitochondria interaction sites and at lipid droplets juxtaposing to perilipin 2

A Gemmink, S Daemen, HJH Kuijpers… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Objective Intramyocellular lipid droplets (LD) and their coat proteins PLIN2 and PLIN5 are
involved in lipolysis, with a putative role for PLIN5 in mitochondrial tethering. Reportedly …

Skeletal muscle lipid droplets and the athlete's paradox

X Li, Z Li, M Zhao, Y Nie, P Liu, Y Zhu, X Zhang - Cells, 2019 - mdpi.com
The lipid droplet (LD) is an organelle enveloped by a monolayer phospholipid membrane
with a core of neutral lipids, which is conserved from bacteria to humans. The available …

The metabolic syndrome, a human disease

M Alemany - International journal of molecular sciences, 2024 - mdpi.com
This review focuses on the question of metabolic syndrome (MS) being a complex, but
essentially monophyletic, galaxy of associated diseases/disorders, or just a syndrome of …

[HTML][HTML] Skeletal muscle in healthy humans exhibits a day-night rhythm in lipid metabolism

NM Held, J Wefers, M van Weeghel, S Daemen… - Molecular …, 2020 - Elsevier
Objective Human energy metabolism is under the regulation of the molecular circadian
clock; we recently reported that mitochondrial respiration displays a day-night rhythm under …

Radial variation in biochemical composition of the bovine caudal intervertebral disc

SE Bezci, B Werbner, M Zhou, KG Malollari… - JOR …, 2019 - Wiley Online Library
Bovine caudal discs have been widely used in spine research due to their increased
availability, large size, and mechanical and biochemical properties that are comparable to …

Exercise Training Differentially Affects Skeletal Muscle Mitochondria in Rats with Inherited High or Low Exercise Capacity

E Heyne, S Zeeb, C Junker, A Petzinna, A Schrepper… - Cells, 2024 - mdpi.com
Exercise capacity has been related to morbidity and mortality. It consists of an inherited and
an acquired part and is dependent on mitochondrial function. We assessed skeletal muscle …