ctDNA applications and integration in colorectal cancer: an NCI Colon and Rectal–Anal Task Forces whitepaper

A Dasari, VK Morris, CJ Allegra, C Atreya… - Nature reviews Clinical …, 2020 - nature.com
An increasing number of studies are describing potential uses of circulating tumour DNA
(ctDNA) in the care of patients with colorectal cancer. Owing to this rapidly developing area …

Current and future clinical applications of ctDNA in immuno-oncology

JC Stadler, Y Belloum, B Deitert, M Sementsov… - Cancer Research, 2022 - AACR
Testing peripheral blood for circulating tumor DNA (ctDNA) offers a minimally invasive
opportunity to diagnose, characterize, and monitor the disease in individual cancer patients …

Day-to-day and within-day biological variation of cell-free DNA

AT Madsen, JA Hojbjerg, BS Sorensen… - …, 2019 - thelancet.com
Background Numerous studies have shown that cell-free DNA (cfDNA) levels may serve as
a non-invasive biomarker of a broad spectrum of acute and chronic pathologies. However, in …

[HTML][HTML] Circulating biomarkers for monitoring therapy response and detection of disease progression in lung cancer patients

R de Kock, B van den Borne, M Youssef-El Soud… - Cancer Treatment and …, 2021 - Elsevier
Liquid biopsies have become of interest as minimally invasive ways to monitor treatment
response in lung cancer patients. Circulating tumor DNA (ctDNA) and protein biomarkers …

Genomic profiling of circulating tumor DNA predicts outcome and demonstrates tumor evolution in ALK-positive non-small cell lung cancer patients

AT Madsen, A Winther-Larsen, T McCulloch… - Cancers, 2020 - mdpi.com
With the rapid development of targeted therapies for the treatment of cancer, methods for
predicting response and outcome are in high demand. Non-small cell lung cancer driven by …

Critical Factors in the Analytical Work Flow of Circulating Tumor DNA-Based Molecular Profiling

P Van Der Leest, E Schuuring - Clinical chemistry, 2024 - academic.oup.com
Background Liquid biopsy testing, especially molecular tumor profiling of circulating tumor
DNA (ctDNA) in cell-free plasma, has received increasing interest in recent years as it …

Dynamics of methylated cell-free DNA in the urine of non-small cell lung cancer patients

S Bach, BMM Wever, MA van de Wiel, JD Veltman… - Epigenetics, 2022 - Taylor & Francis
High levels of methylated DNA in urine represent an emerging biomarker for non-small cell
lung cancer (NSCLC) detection and are the subject of ongoing research. This study aimed to …

[HTML][HTML] Genetic landscape of breast cancer and mutation tracking with circulating tumor DNA in Chinese women

Y Wang, L Lin, L Li, J Wen, Y Chi, R Hao, X Dai… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Considerable efforts have been devoted to exploring the breast cancer mutational
landscape to understand its genetic complexity. However, no studies have yet …

How to obtain a high quality ctDNA in lymphoma patients: preanalytical tips and tricks

E Bourbon, V Alcazer, E Cheli, S Huet, P Sujobert - Pharmaceuticals, 2021 - mdpi.com
The analysis of circulating tumor DNA (ctDNA) released by tumor cells holds great promise
for patients with lymphoma, to refine the diagnostic procedure, clarify the prognosis, monitor …

Reporting on circulating tumor DNA monitoring in metastatic cancer—From clinical validity to clinical utility

C Brenner Thomsen, A Dandanell Juul, AC Lefèvre… - Cancer, 2022 - Wiley Online Library
Reporting on circulating tumor DNA monitoring in metastatic cancer—From clinical validity to
clinical utility - Brenner Thomsen - 2022 - Cancer - Wiley Online Library Skip to Article Content …