Phagocytosis is a cellular process for ingesting and eliminating particles larger than 0.5 μm
in diameter, including microorganisms, foreign substances, and apoptotic cells …

One hundred years have passed since the death of Élie Metchnikoff (1845–1916). He was
the first to observe the uptake of particles by cells and realized the importance of this …

Engulfment and destruction of invading microorganisms by phagocytosis are critical
components of the innate immune response. In addition, phagocytosis is also required for …

Small GTP-binding proteins (G proteins) exist in eukaryotes from yeast to human and
constitute a superfamily consisting of more than 100 members. This superfamily is …

Phagocytosis is a specialized process that enables cellular ingestion and clearance of
microbes, dead cells and tissue debris that are too large for other endocytic routes. As such …

The complement and immunoglobulin receptors are the major phagocytic receptors involved
during infection. However, only immunoglobulin-dependent uptake results in a respiratory …

Abstract αMβ2 integrin (complement receptor 3) is a major receptor for phagocytosis in
macrophages. In other contexts, integrins' activities and functions are mechanically linked to …

Microglia are the principle immune effector and phagocytic cells in the CNS. These cells are
associated with fibrillar β-amyloid (fAβ)-containing plaques found in the brains of …

It has long been known from the results of ultrastructural studies that complement-and
immunoglobulin G (IgG)-opsonized particles are phagocytosed differently by macrophages …

Leptin is an adipocyte-derived hormone that is secreted in correlation with total body lipid
stores. Serum leptin levels are lowered by the loss of body fat mass that would accompany …