CircRNAs, covalently closed noncoding RNAs, are widely expressed in a wide range of
species ranging from viruses to plants to mammals. CircRNAs were enriched in the Wnt …

Parkinson's disease (PD) is a slowly progressive multisystem disorder affecting
dopaminergic neurons of the substantia nigra pars compacta (SNpc), which is characterized …

Neurodegenerative diseases (NDs) affect millions of people worldwide, and to date,
Alzheimer's and Parkinson's diseases are the most common NDs. Of the many risk factors …

CTNNB1 is the gene that encodes β-catenin which acts as a key player in the Wnt signaling
pathway and regulates cellular homeostasis. Most CTNNB1-related studies have been …

Ever since their discoveries, the Wnt pathways have been consistently associated with key
features of cellular development, including metabolism, structure and cell fate. The three …

Hippocampal neurogenesis is known to be related to depressive symptoms. Increasing
evidence indicates that Wnt/β-catenin signaling regulates multiple aspects of adult …

Neurogenesis and tumorigenesis share signaling molecules/pathways involved in cell
proliferation, differentiation, migration, and death. Self-renewal of neural stem cells is a …

Autism spectrum disorder (ASD) is a neurodevelopmental disorder associated with impaired
social behavior and communication, repetitive behaviors, and restricted interests. In addition …

Alzheimer's disease (AD) is a major form of dementia. Abnormal amyloidogenic event-
mediated degeneration of cholinergic neurons in the cognitive centers of the brain has been …

The generation of new neurons in the adult brain is a currently accepted phenomenon. Over
the past few decades, the subventricular zone and the hippocampal dentate gyrus have …