Dynamics of ACTH and cortisol secretion and implications for disease

SL Lightman, MT Birnie… - Endocrine …, 2020 - academic.oup.com
The past decade has seen several critical advances in our understanding of hypothalamic–
pituitary–adrenal (HPA) axis regulation. Homeostatic physiological circuits need to integrate …

Neoplasms of the neuroendocrine pancreas: an update in the classification, definition, and molecular genetic advances

JM Guilmette, V Nosé - Advances in anatomic pathology, 2019 - journals.lww.com
This review focuses on discussing the main modifications of the recently published 2017
WHO Classification of Neoplasms of the Neuroendocrine Pancreas (panNEN). Recent …

[PDF][PDF] Impacts of plastic pollution on the sustainability of seafood value chain and human health

CG Awuchi, CG Awuchi - International Journal of Advanced Academic …, 2019 - ijaar.org
The study evaluated the impacts of plastic pollution on the sustainability of seafood value
chain. The world aquaculture production in 2016 stood at 80.0 million tons of food fish …

Cushing's disease

H Nishioka, S Yamada - Journal of clinical medicine, 2019 - mdpi.com
In patients with Cushing's disease (CD), prompt diagnosis and treatment are essential for
favorable long-term outcomes, although this remains a challenging task. The differential …

Surgical therapy of adrenal tumors: guidelines from the German Association of Endocrine Surgeons (CAEK)

K Lorenz, P Langer, B Niederle, P Alesina… - … archives of surgery, 2019 - Springer
Background and aims Previous guidelines addressing surgery of adrenal tumors required
actualization in adaption of developments in the area. The present guideline aims to provide …

Targeting PD-L1 initiates effective antitumor immunity in a murine model of Cushing disease

HR Kemeny, AA Elsamadicy, SH Farber… - Clinical Cancer …, 2020 - AACR
Purpose: Although pituitary adenoma is classified as benign, Cushing disease is associated
with significant morbidity due to the numerous sequelae of elevated cortisol levels …

Endocrine system

DM Janz - The laboratory fish, 2000 - Elsevier
Publisher Summary This chapter provides an overview of teleost endocrine physiology in
terms of both the diverse and conserved nature of hormones in fishes. Techniques available …

Adrenodoxin allosterically alters human cytochrome P450 11B enzymes to accelerate substrate binding and decelerate release

CL Loomis, SC Im, EE Scott - RSC Chemical Biology, 2024 - pubs.rsc.org
Two human mitochondrial membrane CYP11B enzymes play a pivotal role in
steroidogenesis. CYP11B1 generates the major glucocorticoid cortisol, while CYP11B2 …

Outcome of transsphenoidal surgery for Cushing disease: a single-center experience over 20 years

C Brichard, E Costa, E Fomekong, D Maiter… - World neurosurgery, 2018 - Elsevier
Background This study investigated the outcome of transsphenoidal surgery (TSS) for
Cushing disease (CD) and the influence of our surgical strategy on remission rates and …

Expression of EGFR in pituitary corticotroph adenomas and its relationship with tumor behavior

X Liu, M Feng, C Dai, X Bao, K Deng, Y Yao… - Frontiers in …, 2019 - frontiersin.org
Objective: Epidermal growth factor receptor (EGFR) has been found to localize in several
human neoplasms and has been shown to have a significant correlation with …