An ever-increasing demand for novel antimicrobials to treat life-threatening infections
caused by the global spread of multidrug-resistant bacterial pathogens stands in stark …

The pulmonary microbial community, described only a few years ago, forms a discreet part
of the human host microbiota. The airway microbiota has been found to be substantially …

Antibiotics are deployed against bacterial pathogens, but their targeting of conserved
microbial processes means they also collaterally perturb the commensal microbiome. To …

Human body surfaces, such as the skin, intestines, and respiratory and urogenital tracts, are
colonized by a large number of microorganisms, including bacteria, fungi, and viruses, with …

The microbiota-gut-brain axis is a bidirectional communication system that is poorly
understood. Alzheimer's disease (AD), the most common cause of dementia, has long been …

The efficacy of drugs widely varies in individuals, and the gut microbiota plays an important
role in this variability. The commensal microbiota living in the human gut encodes several …

Microbiome research has increased dramatically in recent years, driven by advances in
technology and significant reductions in the cost of analysis. Such research has unlocked a …

While broad spectrum antibiotics play an invaluable role in the treatment of bacterial
infections, there are some drawbacks to their use, namely selection for and spread of …

Cross talk occurs between the human gut and the lung through a gut-lung axis involving the
gut microbiota. However, the signatures of the human gut microbiota after active …

Background: An improved understanding of the gut microbiota could lead to better strategies
for the diagnosis, therapy and prophylaxis of tuberculosis (TB). The impact of both …