Rheumatoid arthritis (RA) is a chronic, inflammatory, systemic autoimmune disease,
affecting the joints with varying severity among patients. The risk factors include age …

Endocrine homeostasis and metabolic diseases have been the subject of extensive
research in recent years. The development of new techniques and insights has led to a …

Transcriptomics, the high-throughput characterization of RNAs, has been instrumental in
defining pathogenic signatures in human autoimmunity and autoinflammation. It enabled the …

Personalized medicine encompasses a broad and evolving field informed by a patient
distinctive information and biomarker profile. Although terminology is evolving and some …

Introduction Systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and Sjögren's
syndrome (SjS) are inflammatory systemic autoimmune diseases (SADs) that share several …

Rheumatoid arthritis is an autoimmune disease that affects several organs and tissues,
predominantly the synovial joints. The pathogenesis of this disease is not completely …

Individualising biologic disease-modifying anti-rheumatic drugs (bDMARDs) to maximise
outcomes and deliver safe and cost-effective care is a key goal in the management of …

Biomarkers are needed to guide treatment decisions for patients with rheumatic diseases.
Although the phenotypic and functional analysis of immune cells is an appealing strategy for …

Background Metabolomics is an emerging field of biomedical research that may offer a
better understanding of the mechanisms of underlying conditions including inflammatory …

Background According to EULAR recommendations, biologic DMARDs (bDMARDs) such as
tumor necrosis factor inhibitor, tocilizumab (TCZ), and abatacept (ABT) are in parallel when …