Ischemia/reperfusion (I/R) injury is associated with substantial clinical implications, including
a wide range of organs such as the brain, kidneys, lungs, heart, and many others. I/R injury …

The cytokine storm is a marker of severity of various diseases and increased mortality. The
altered metabolic profile and energy generation of immune cells affects their activation …

Background As a leading cause of vision decline and severe blindness in adults, diabetic
retinopathy (DR) is characterized by the aggravation of retinal oxidative stress and apoptosis …

Excess reactive oxygen species (ROS) can induce serious acute kidney injury (AKI) to result
in numerous deaths annually in clinical practice. Elimination of excess ROS by advanced …

Acute kidney injury (AKI) results from the rapid deterioration of renal function, which is
mainly treated by transplantation and dialysis, and has a high mortality rate. Inflammation …

Mangiferin (Mang) is a known glucosylxanthone that has proven its shielding effect against
ischemia/reperfusion (Is/R). However, its full underlying mechanistic perspective against …

In 2020, a group of experts officially suggested metabolic dysfunction associated with fatty
liver disease “MAFLD” as a more appropriate overarching term than NAFLD, indicating the …

Pancreatic cancer (PC) is a lethal malignancy cancer, and its mortality rates have been
increasing worldwide. Diagnosis of this cancer is complicated, as it does not often present …

Microbiome dysbiosis resulting in altered metabolite profiles may be associated with certain
diseases, including inflammatory bowel diseases (IBD), which are characterized by active …

Effective and targeted prevention and treatment methods for acute kidney injury (AKI), a
common clinical complication, still needs to be explored. Paricalcitol is a biologically active …