Thyroid hormones, oxidative stress, and inflammation

A Mancini, C Di Segni, S Raimondo… - Mediators of …, 2016 - Wiley Online Library
Inflammation and oxidative stress (OS) are closely related processes, as well exemplified in
obesity and cardiovascular diseases. OS is also related to hormonal derangement in a …

Phycocyanobilin is the molecule responsible for the nephroprotective action of phycocyanin in acute kidney injury caused by mercury

E Garcia-Pliego, M Franco-Colin, P Rojas-Franco… - Food & Function, 2021 - pubs.rsc.org
C-Phycocyanin (CPC) exerts therapeutic, antioxidant, anti-inflammatory and
immunomodulatory actions. It prevents oxidative stress and acute kidney damage caused by …

Vitamin E management of oxidative damage-linked dysfunctions of hyperthyroid tissues

P Venditti, L Di Stefano, S Di Meo - Cellular and Molecular Life Sciences, 2013 - Springer
Introduction Thyroid hormones affect growth, development, and metabolism of vertebrates,
and are considered the major regulators of their homeostasis. On the other hand, elevated …

Protective effects of GM-CSF in experimental neonatal hypothyroidism

RG Ahmed, M Abdel-Latif, F Ahmed - International Immunopharmacology, 2015 - Elsevier
Hypothyroidism induced by methimazole (MMI), has a negative impact on the postnatal
development. Neonatal Granulocyte Macrophage-Colony Stimulating Factor [GM-CSF; 50 …

Protective Effect of Epigallocatechin‐3‐Gallate in Hydrogen Peroxide‐Induced Oxidative Damage in Chicken Lymphocytes

X Chi, X Ma, Z Li, Y Zhang, Y Wang… - Oxidative Medicine …, 2020 - Wiley Online Library
Epigallocatechin‐3‐gallate (EGCG) is one of the fundamental compounds in green tea. The
present study was to evaluate the protective effect of EGCG in oxidative damage and …

Dietary-induced chronic hypothyroidism negatively affects rat follicular development and ovulation rate and is associated with oxidative stress

L Meng, E Rijntjes, H Swarts, A Bunschoten… - Biology of …, 2016 - academic.oup.com
The long-term effects of chronic hypothyroidism on ovarian follicular development in
adulthood are not well known. Using a rat model of chronic diet-induced hypothyroidism …

Thyroid disrupting pesticides mancozeb and fipronil in mixture caused oxidative damage and genotoxicity in lymphoid organs of mice

F Bano, B Mohanty - Environmental Toxicology and Pharmacology, 2020 - Elsevier
The interference in endocrine signaling in particular of hypothyroid-pituitary-thyroid axis
during embryonic/neonatal development increases the risk of long-lasting immune …

Endoplasmic reticulum stress participates in the pathophysiology of mercury-caused acute kidney injury

P Rojas-Franco, M Franco-Colín, AP Torres-Manzo… - Renal …, 2019 - Taylor & Francis
Acute exposure to mercury chloride (HgCl2) causes acute kidney injury (AKI). Some metals
interfere with protein folding, leading to endoplasmic reticulum stress (ERS), and the …

Research briefing

M Noseda, SA Teichmann - Nature Medicine, 2024 - nature.com
The vascular system has many different functions across the human body beyond its role in
oxygen and nutrient transport. We explored vascular cell heterogeneity by integrating single …

Predicting Drugs Suspected of Causing Adverse Drug Reactions Using Graph Features and Attention Mechanisms

J Yang, Z Hu, L Zhang, B Peng - Pharmaceuticals, 2024 - mdpi.com
Background: Adverse drug reactions (ADRs) refer to an unintended harmful reaction that
occurs after the administration of a medication for therapeutic purposes, which is unrelated …