Behavioural phenotypes in the cuprizone model of central nervous system demyelination

MK Sen, DA Mahns, JR Coorssen… - … & Biobehavioral Reviews, 2019 - Elsevier
The feeding of cuprizone (CPZ) to animals has been extensively used to model the
processes of demyelination and remyelination, with many papers adopting a narrative linked …

Multiple sclerosis identification by convolutional neural network with dropout and parametric ReLU

YD Zhang, C Pan, J Sun, C Tang - Journal of computational science, 2018 - Elsevier
Multiple sclerosis is a condition affecting brain and/or spinal cord. Based on deep learning,
this study aims to develop an improved convolutional neural network system. We collected …

Immune tolerance in multiple sclerosis and neuromyelitis optica with peptide-loaded tolerogenic dendritic cells in a phase 1b trial

I Zubizarreta, G Flórez-Grau, G Vila… - Proceedings of the …, 2019 - National Acad Sciences
There are adaptive T-cell and antibody autoimmune responses to myelin-derived peptides
in multiple sclerosis (MS) and to aquaporin-4 (AQP4) in neuromyelitis optica spectrum …

Case for a new corticosteroid treatment trial in optic neuritis: review of updated evidence

A Petzold, T Braithwaite, BW van Oosten… - Journal of Neurology …, 2020 - jnnp.bmj.com
Optic neuritis (ON) is a condition that causes loss of vision. Most frequently, ON affects one
eye, but occasionally, simultaneous bilateral loss of vision occurs. Typically, a variable …

[HTML][HTML] Transcutaneous spinal cord stimulation improves postural stability in individuals with multiple sclerosis

BWR Roberts, DA Atkinson, GA Manson… - Multiple sclerosis and …, 2021 - Elsevier
Background Widespread demyelination in the central nervous system can lead to
progressive sensorimotor impairments following multiple sclerosis, with compromised …

Design and validation of an expanded disability status scale model in multiple sclerosis

A Barreiro-González, MT Sanz, S Carratalà-Boscà… - European …, 2022 - karger.com
Introduction: We aimed to develop and validate an Expanded Disability Status Scale (EDSS)
model through clinical, optical coherence tomography (OCT), and magnetic resonance …

[HTML][HTML] Retinal nerve fiber layer thickness correlates with serum and cerebrospinal fluid neurofilament levels and is associated with current disability in multiple …

C Uzunköprü, N Yüceyar, SG Yilmaz… - Archives of …, 2021 - ncbi.nlm.nih.gov
Method: We quantified serum (s) and/or cerebrospinal fluid (CSF) NfH and NT levels in 30
relapsing-remitting MS patients (RRMS), 16 secondary progressive MS (SPMS) patients and …

Improved particle swarm optimized deep convolutional neural network with super‐pixel clustering for multiple sclerosis lesion segmentation in brain MRI imaging

R Krishna Priya, S Chacko - International Journal for Numerical …, 2021 - Wiley Online Library
A central nervous system (CNS) disease affecting the insulating myelin sheaths around the
brain axons is called multiple sclerosis (MS). In today's world, MS is extensively diagnosed …

Ocular and inflammatory markers associated with Gulf War illness symptoms

K Kalahasty, Y Lee, E Locatelli, M Djulbegovic… - Scientific reports, 2023 - nature.com
To examine the utility of ocular coherence tomography (OCT) metrics, in conjunction with
systemic markers of inflammation, in identifying individuals with Gulf War Illness (GWI) …

Optical coherence tomography: a useful tool for identifying subclinical optic neuropathy in diagnosing multiple sclerosis

P Villoslada, B Sanchez-Dalmau, S Galetta - Neurology, 2020 - AAN Enterprises
Care of patients with multiple sclerosis (MS) has evolved in the last decade to shorten the
time to confirm the diagnosis of clinically definite MS and to start disease-modifying drugs as …