Major advances have been made in our understanding of the role of apolipoprotein E
(apoE) in the onset and development of atherosclerosis. Increasing evidence from both …

Cardiovascular risk is determined by the complex interactions between genetic and
environmental factors. The apoE genotype represents the most-widely-studied single …

The study assessed the efficacy of fish oil supplementation in counteracting the classic
dyslipidemia of the atherogenic lipoprotein phenotype (ALP). In addition, the impact of the …

Background: n− 3 Fatty acids lower plasma triacylglycerols not only in the fasting state but
also in the postprandial state. However, it is not known whether chylomicrons, chylomicron …

We propose the hypothesis that small high‐density lipoprotein (HDL) particles reduce the
risk of Alzheimer's disease (AD) by virtue of their capacity to exchange lipids, affecting …

An elevated low-density lipoprotein cholesterol concentration is a classical risk factor for
cardiovascular disease. This has led to pharmacotherapy in patients with atherosclerotic …

Genetic polymorphism in human populations is part of the evolutionary process that results
from the interaction between the environment and the human genome. Recent changes in …

CHD is a multifactorial disease that is associated with non-modifiable risk factors, such as
age, gender and genetic background, and with modifiable risk factors, including elevated …

Purpose “Quantile-dependent expressivity” describes an effect of the genotype that depends
upon the level of the phenotype (eg, whether a subject's triglycerides are high or low relative …

Plasma concentrations of lipids, lipoproteins, and apolipoproteins (apo) are established risk
factors for coronary heart disease (CHD). The knowledge of lipid profile may predict the …