Immunogenic cell death in cancer therapy: Present and emerging inducers

J Zhou, G Wang, Y Chen, H Wang… - Journal of cellular and …, 2019 - Wiley Online Library
In the tumour microenvironment (TME), immunogenic cell death (ICD) plays a major role in
stimulating the dysfunctional antitumour immune system. Chronic exposure of damage …

Traditional Chinese medicine as a cancer treatment: Modern perspectives of ancient but advanced science

Y Xiang, Z Guo, P Zhu, J Chen, Y Huang - Cancer medicine, 2019 - Wiley Online Library
Traditional Chinese medicine (TCM) has been practiced for thousands of years and at the
present time is widely accepted as an alternative treatment for cancer. In this review, we …

Icaritin exacerbates mitophagy and synergizes with doxorubicin to induce immunogenic cell death in hepatocellular carcinoma

Z Yu, J Guo, M Hu, Y Gao, L Huang - Acs Nano, 2020 - ACS Publications
Hepatocellular carcinoma (HCC) resistant to both chemotherapy and immunotherapy is
among the deadliest malignancies. Doxorubicin widely used in transarterial chemotherapy …

Recent advances in engineered materials for immunotherapy‐involved combination cancer therapy

JL Liang, GF Luo, WH Chen, XZ Zhang - Advanced Materials, 2021 - Wiley Online Library
Immunotherapy that can activate immunity or enhance the immunogenicity of tumors has
emerged as one of the most effective methods for cancer therapy. Nevertheless, single …

Traditional herbal medicine and nanomedicine: Converging disciplines to improve therapeutic efficacy and human health

J Zhang, K Hu, L Di, P Wang, Z Liu, J Zhang… - Advanced drug delivery …, 2021 - Elsevier
Traditional herbal medicine (THM), an ancient science, is a gift from nature. For thousands of
years, it has helped humans fight diseases and protect life, health, and reproduction …

Manganese-Based Nanoactivator Optimizes Cancer Immunotherapy via Enhancing Innate Immunity

L Hou, C Tian, Y Yan, L Zhang, H Zhang, Z Zhang - ACS nano, 2020 - ACS Publications
Cyclic GMP-AMP synthase (cGAS) and stimulator of interferon genes (STING) are essential
components of the innate immune sensors to cytosolic DNA and elicit type I interferon (IFN) …

Nano delivery of chemotherapeutic ICD inducers for tumor immunotherapy

J Guo, Y Zou, L Huang - Small Methods, 2023 - Wiley Online Library
Immunogenic cell death (ICD, also known as immunogenic apoptosis) of malignant cells is
confirmed to activate the host immune system to prevent, control, and eliminate tumors …

Trial watch: chemotherapy-induced immunogenic cell death in immuno-oncology

I Vanmeerbeek, J Sprooten, D De Ruysscher… - …, 2020 - Taylor & Francis
The term 'immunogenic cell death'(ICD) denotes an immunologically unique type of
regulated cell death that enables, rather than suppresses, T cell-driven immune responses …

Nano codelivery of oxaliplatin and folinic acid achieves synergistic chemo-immunotherapy with 5-fluorouracil for colorectal cancer and liver metastasis

J Guo, Z Yu, M Das, L Huang - ACS nano, 2020 - ACS Publications
FOLFOX, the combinational strategy of folinic acid (FnA), 5-fluorouracil (5-Fu), and
oxaliplatin (OxP), has been used as standard treatment of colorectal cancer (CRC) for …

Photothermal-chemotherapy enhancing tumor immunotherapy by multifunctional metal–organic framework based drug delivery system

W Ni, J Wu, H Fang, Y Feng, Y Hu, L Lin, J Chen… - Nano Letters, 2021 - ACS Publications
Immunotherapy holds great promise for patients undergoing tumor treatment. However, the
clinical effect of immunotherapy is limited because of tumor immunogenicity and its …