Point-of-care microfluidic devices for pathogen detection

B Nasseri, N Soleimani, N Rabiee, A Kalbasi… - Biosensors and …, 2018 - Elsevier
The rapid diagnosis of pathogens is crucial in the early stages of treatment of diseases
where the choice of the correct drug can be critical. Although conventional cell culture-based …

The antigenic structure of Zika virus and its relation to other flaviviruses: implications for infection and immunoprophylaxis

FX Heinz, K Stiasny - Microbiology and Molecular Biology …, 2017 - Am Soc Microbiol
Zika virus was discovered∼ 70 years ago in Uganda and maintained a low profile as a
human disease agent in Africa and Asia. Only recently has it caused explosive outbreaks in …

Congenital Zika virus infection: beyond neonatal microcephaly

AS de Oliveira Melo, RS Aguiar, MMR Amorim… - JAMA …, 2016 - jamanetwork.com
Importance Recent studies have reported an increase in the number of fetuses and
neonates with microcephaly whose mothers were infected with the Zika virus (ZIKV) during …

Mapping and role of the CD8+ T cell response during primary Zika virus infection in mice

AE Ngono, EA Vizcarra, WW Tang, N Sheets, Y Joo… - Cell host & …, 2017 - cell.com
CD8+ T cells may play a dual role in protection against and pathogenesis of flaviviruses,
including Zika virus (ZIKV). We evaluated the CD8+ T cell response in ZIKV-infected …

Silver nanoparticles as potential antiviral agents

ZA Ratan, FR Mashrur, AP Chhoan, SM Shahriar… - Pharmaceutics, 2021 - mdpi.com
Since the early 1990s, nanotechnology has led to new horizons in nanomedicine, which
encompasses all spheres of science including chemistry, material science, biology, and …

Proteomics and integrative omic approaches for understanding host–pathogen interactions and infectious diseases

PM Jean Beltran, JD Federspiel, X Sheng… - Molecular systems …, 2017 - embopress.org
Organisms are constantly exposed to microbial pathogens in their environments. When a
pathogen meets its host, a series of intricate intracellular interactions shape the outcome of …

The spectrum of neuropathological changes associated with congenital Zika virus infection

L Chimelli, ASO Melo, E Avvad-Portari, CA Wiley… - Acta …, 2017 - Springer
A major concern associated with ZIKV infection is the increased incidence of microcephaly
with frequent calcifications in infants born from infected mothers. To date, postmortem …

Dynamic forecasting of Zika epidemics using Google Trends

Y Teng, D Bi, G Xie, Y Jin, Y Huang, B Lin, X An… - PloS one, 2017 - journals.plos.org
We developed a dynamic forecasting model for Zika virus (ZIKV), based on real-time online
search data from Google Trends (GTs). It was designed to provide Zika virus disease (ZVD) …

Arbidol (Umifenovir): a broad-spectrum antiviral drug that inhibits medically important arthropod-borne flaviviruses

J Haviernik, M Štefánik, M Fojtíková, S Kali, N Tordo… - Viruses, 2018 - mdpi.com
Arthropod-borne flaviviruses are human pathogens of global medical importance, against
which no effective small molecule-based antiviral therapy has currently been reported …

Zika virus: An emergent neuropathological agent

MK White, HS Wollebo, J David Beckham… - Annals of …, 2016 - Wiley Online Library
The emergence of Zika virus in the Americas has followed a pattern that is familiar from
earlier epidemics of other viruses, where a new disease is introduced into a human …