Dendritic cells (DCs) are antigen-presenting cells with a unique ability to induce primary
immune responses. DCs capture and transfer information from the outside world to the cells …

▪ Abstract The conversion of exogenous and endogenous proteins into immunogenic
peptides recognized by T lymphocytes involves a series of proteolytic and other enzymatic …

Dendritic cells (DCs) initiate and control immune responses. Plasmacytoid DCs (pDCs)
represent a unique DC subset able to promptly release large amounts of type I interferon …

CD34+ cells in human cord blood and marrow are known to give rise to dendritic cells (DC),
as well as to other myeloid lineages. CD34+ cells are rare in adult blood, however, making it …

Mouse studies have shown that the immune system can reject tumours, and the
identification of tumour antigens that can be recognized by human T cells has facilitated the …

DCs (dendritic cells) function as sentinels of the immune system. They traffic from the blood
to the tissues where, while immature, they capture antigens. They then leave the tissues and …

Experimental autoimmune encephalomyelitis (EAE) is an animal model for autoimmune
central nervous system disease mediated by CD4 T cells. To examine the role of B cells in …

It is now possible to grow DC-like cells in culture17-21 and extensive cell membrane
processes that are acquired late the first monoclonal antibodies (MoAbs) 22, 23 that react …

DENDRITIC cells comprise a system of highly efficient antigen-presenting cells which initiate
immune responses such as the sensitization of T cells restricted by major histocompatibility …

Alum has been the most widely used adjuvant for over 80 years. Although there have been
searches for alternative adjuvants, aluminium-containing adjuvants will continue to be used …