Recent developments in bioprocessing of recombinant proteins: expression hosts and process development

NK Tripathi, A Shrivastava - Frontiers in Bioengineering and …, 2019 - frontiersin.org
Infectious diseases, along with cancers, are among the main causes of death among
humans worldwide. The production of therapeutic proteins for treating diseases at large …

Valuable pigments from microalgae: phycobiliproteins, primary carotenoids, and fucoxanthin

G Chini Zittelli, R Lauceri, C Faraloni… - Photochemical & …, 2023 - Springer
Phycobiliproteins, carotenoids and fucoxanthin are photosynthetic pigments extracted from
microalgae and cyanobacteria with great potential biotechnological applications, as healthy …

[HTML][HTML] Bioprocess intensification: A route to efficient and sustainable biocatalytic transformations for the future

KVK Boodhoo, MC Flickinger, JM Woodley… - … and Processing-Process …, 2022 - Elsevier
With the current pressing need to rise to the ambition of net zero targets to mitigate carbon
emissions and climate change impacts, sustainable processing has never been more …

Development of L-asparaginase biobetters: current research status and review of the desirable quality profiles

LP Brumano, FVS da Silva, TA Costa-Silva… - … in bioengineering and …, 2019 - frontiersin.org
L-Asparaginase (ASNase) is a vital component of the first line treatment of acute
lymphoblastic leukemia (ALL), an aggressive type of blood cancer expected to afflict over …

Seaweed protein hydrolysates and bioactive peptides: Extraction, purification, and applications

J Echave, M Fraga-Corral, P Garcia-Perez… - Marine drugs, 2021 - mdpi.com
Seaweeds are industrially exploited for obtaining pigments, polysaccharides, or phenolic
compounds with application in diverse fields. Nevertheless, their rich composition in fiber …

Bacterial inclusion bodies: a treasure trove of bioactive proteins

P Singhvi, A Saneja, S Srichandan, AK Panda - Trends in Biotechnology, 2020 - cell.com
Recombinant proteins expressed as bacterial inclusion bodies (IBs) are now receiving
tremendous attention for many diverse applications in the areas of industrial and medical …

Towards a digital bioprocess replica: computational approaches in biopharmaceutical development and manufacturing

J Smiatek, A Jung, E Bluhmki - Trends in Biotechnology, 2020 - cell.com
Quantitative unit operation models for the optimization and refinement of modern late-stage
biopharmaceutical drug manufacturing processes have recently attracted increasing …

[图书][B] Liquid chromatography: applications

S Fanali, PR Haddad, C Poole, ML Riekkola - 2017 - books.google.com
Liquid Chromatography: Applications, Second Edition, is a single source of authoritative
information on all aspects of the practice of modern liquid chromatography. It gives those …

Messenger RNA chromatographic purification: advances and challenges

X Feng, Z Su, Y Cheng, G Ma, S Zhang - Journal of Chromatography A, 2023 - Elsevier
Messenger RNA (mRNA) technologies have shown great potential in prophylactic vaccines
and therapeutic medicines due to their adaptability, rapidity, efficacy, and safety. The purity …

Analyzing and understanding the robustness of bioprocesses

L Becker, J Sturm, F Eiden, D Holtmann - Trends in Biotechnology, 2023 - cell.com
The robustness of bioprocesses is becoming increasingly important. The main driving forces
of this development are, in particular, increasing demands on product purities as well as …