Hepatitis B and D virus entry

K Watashi, K Shionoya, C Kobayashi… - Nature Reviews …, 2024 - nature.com
Hepatitis B virus (HBV) entry is the initial step of viral infection, leading to the formation of
covalently closed circular DNA, which is a molecular reservoir of viral persistence and a key …

[HTML][HTML] Targeting NTCP for liver disease treatment: A promising strategy

X Tan, Y Xiang, J Shi, L Chen, D Yu - Journal of Pharmaceutical Analysis, 2024 - Elsevier
The sodium taurocholate co-transporting polypeptide (NTCP), a bile acids transporter, has
been identified as a new therapeutic target for the treatment of liver disease. This paper …

Aspartate transaminase to platelet ratio index and gamma‐glutamyl transpeptidase‐to‐platelet ratio outweigh fibrosis index based on four factors and red cell …

X Wu, B Cai, Z Su, Y Li, J Xu, R Deng… - Journal of clinical …, 2018 - Wiley Online Library
Background The benefits of using serum markers to diagnose stages of liver disease in
chronic hepatitis B (CHB) patients are controversial. We conducted a study to compare the …

Evolution of hepatitis B virus receptor NTCP reveals differential pathogenicities and species specificities of hepadnaviruses in primates, rodents, and bats

S Jacquet, JB Pons, A De Bernardo… - Journal of …, 2019 - Am Soc Microbiol
Human hepatitis B virus (HBV) is a global health problem, affecting more than 250 million
people worldwide. HBV-like viruses, named orthohepadnaviruses, also naturally infect …

[HTML][HTML] Genetic variations of NTCP are associated with susceptibility to HBV infection and related hepatocellular carcinoma

P Wang, R Mo, R Lai, Y Xu, J Lu, G Zhao, Y Liu, Z Cao… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Sodium taurocholate cotransporting polypeptide (NTCP), encoded by gene SLC10A1, is a
receptor for hepatitis B virus (HBV). The aim of the current study was to investigate the role of …

Association of NTCP polymorphisms with clinical outcome of hepatitis B infection in Thai individuals

N Chuaypen, N Tuyapala, N Pinjaroen… - BMC medical …, 2019 - Springer
Abstract Background Single nucleotide polymorphisms (SNPs) in the sodium taurocholate
co-transporting polypeptide (NTCP) have been showed to be associated with natural history …

The relationship between NTCP gene varieties and the progress of liver disease after HBV infection: an updated systematic review and meta-analysis

C He, HY He, CF Sun, SC Ojha, H Wang… - The American Journal of …, 2022 - Elsevier
Background The aim of this study was to analyze the relationship between sodium
taurocholate cotransporting polypeptide (NTCP) gene varieties and hepatitis B virus (HBV) …

Hepatitis B virus infection in Taiwan: the role of NTCP rs2296651 variant in relation to sex

ON Nfor, MF Wu, T Debnath, CT Lee… - Journal of viral …, 2018 - Wiley Online Library
Sodium taurocholate cotransporting polypeptide (NTCP) is a functional receptor for hepatitis
B virus (HBV) infection. NTCP rs2296651 is believed to be an Asian‐specific variant …

Lack of Ser267Phe variant of sodium taurocholate cotransporting polypeptide among Moroccans regardless of hepatitis B virus infection status

S Ezzikouri, H Chihab, A Elhabazi, L Wakrim… - BMC infectious …, 2017 - Springer
Background The sodium taurocholate co-transporting polypeptide, encoded by SLC10A1,
was identified as a functional receptor for hepatitis B virus (HBV). The objective of this study …

Genetic variants of NTCP gene and hepatitis B vaccine failure in Taiwanese children of hepatitis B e antigen positive mothers

YH Chen, DJ Tsuei, MW Lai, WH Wen, CL Chiang… - Hepatology …, 2022 - Springer
Background and aims Hepatitis B virus (HBV) vaccine failure remains a hurdle to the global
elimination of HBV infections in the vaccination era. We aimed to elucidate the relationships …