In the mature brain, GABA (γ-aminobutyric acid) functions primarily as an inhibitory
neurotransmitter. But it can also act as a trophic factor during nervous system development …

Glycine exerts multiple functions in the central nervous system, as an inhibitory
neurotransmitter through activation of specific, Cl−-permeable, ligand-gated ionotropic …

Inhibitory glycine receptors (GlyRs) regulate motor coordination and sensory signal
processing in spinal cord and other brain regions. GlyRs are pentameric proteins composed …

Glycine and GABA, the dominant inhibitory neurotransmitters in the CNS, assume a
depolarizing role in early development, leading to increased cytoplasmic Ca2+ levels and …

Motoneurons axotomized by peripheral nerve injuries experience profound changes in their
synaptic inputs that are associated with a neuroinflammatory response that includes local …

Neuronal activity in the respiratory network is functionally dependent on inhibitory synaptic
transmission. Using two-photon excitation microscopy, we analyzed the integration of …

In the brain, neurons and glial cells compete for the uptake of the fast neurotransmitters,
glutamate, GABA and glycine, through specific transporters. The relative contributions of glia …

The first two postnatal weeks are the most dynamic in the development of brain stem
respiratory nuclei in the rat, the primary model for this review. Several neurochemicals …

Spontaneous bioelectric activity (SBA) taking the form of extracellularly recorded spike trains
(SBA) has been quantitatively analyzed in organotypic neonatal rat visual cortex explants at …

Previously, we reported that the expression of cytochrome oxidase in a number of brain stem
nuclei exhibited a plateau or reduction at postnatal day (P) 3–4 and a dramatic decrease at …